1,3-Diphenylguanidine Chemical Properties

Melting point:

146-148 °C(lit.)

Boiling point:

170°C

Density 

1,13 g/cm³

vapor pressure 

0Pa at 25℃

refractive index 

1.6000 (estimate)

Flash point:

170°C

storage temp. 

Sealed in dry,Store in freezer, under -20°C

solubility 

Soluble in alcohol, chloroform, hot benzene, hot toluene, and dilute mineral acids

form 

Powder

pka

pK1:10.12 (25°C)

color 

Pale Cream

PH

10.2 (10g/l, H2O)

Odor

wh. powd., bitter taste, sl. odor

Water Solubility 

slightly soluble

Merck 

14,3324

BRN 

1875653

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents. Moisture sensitive.

InChIKey

OWRCNXZUPFZXOS-UHFFFAOYSA-N

LogP

2.42 at 21.1℃

CAS DataBase Reference

102-06-7(CAS DataBase Reference)

NIST Chemistry Reference

Guanidine, n,n'-diphenyl-(102-06-7)

EPA Substance Registry System

1,3-Diphenylguanidine (102-06-7)

Safety Information

Hazard Codes 

Xn,N,T

Risk Statements 

22-36/37/38-51/53-62-25

Safety Statements 

26-36/37/39-61-45

RIDADR 

UN 3077 9/PG 3

WGK Germany 

2

RTECS 

MF0875000

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29252000

Hazardous Substances Data

102-06-7(Hazardous Substances Data)

Toxicity

LD50 oral in rabbit: 250mg/kg

MSDS

• Language:English Provider:1,3-Diphenylguanidine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1,3-Diphenylguanidine Usage And Synthesis

Chemical Properties

1,3-diphenylguanidine is a white or cream powder with a slight odour and bitter taste. slightly soluble in water, soluble in ethanol, chloroform, hot benzene, hot toluene, easily soluble in dilute inorganic acids. Used as medium speed accelerator for natural rubber and synthetic rubber, mainly used in the manufacture of tires, rubber plates, rubber shoes and other rubber industrial products.

Uses

N,N'-Diphenylguanidine is a primary standard for acids; aeeelerator for the vulcanization of rubber for use with thiazoles and sulfenamides; complexing agent in the deteetion of metals and organie bases.

Uses

1,3-Diphenylguanidine is used as pharmaceutical intermediate.

Definition

ChEBI: 1,3-diphenylguanidine is guanidine carrying a phenyl substituent on each of the two amino groups. It is used as an accelerator in the rubber industry. It has a role as an allergen.

General Description

White to cream-colored chalky powder. Bitter taste and slight odor.

Air & Water Reactions

Sensitive to moisture. Aqueous solutions are strongly alkaline. Insoluble in water.

Reactivity Profile

1,3-Diphenylguanidine behaves as an amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. 1,3-Diphenylguanidine is incompatible with strong oxidizers.

Fire Hazard

1,3-Diphenylguanidine is combustible.

Flammability and Explosibility

Non flammable

Contact allergens

Diphenylguanidine is a rubber sensitizer that can induce immediate-type reactions and delayed-type contact allergy. It was formerly contained in “carba mix.” Occupational exposure concerns finished rubber items and the rubber manufacturing industry. The most frequent occupational categories are metal industry, homemakers, health services and laboratories, and the building industry.

Safety Profile

Poison by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

Purification Methods

1,3-Diphenylguanidine [102-06-7] M 211.3, m 148o, 10.12. Crystallise it from toluene,

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