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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Biochemical Reagents >  (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID

(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID

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(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Basic information

Product Name:
(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
Synonyms:
  • (RS)-CPP
  • (RS)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
  • (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
  • DL-CPP
  • (+/-)-CPP
  • (+/-)-CPP POTENT AND SELECTIVE
  • 2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-
  • 2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-, (+-)-
CAS:
100828-16-8
MF:
C8H17N2O5P
MW:
252.2
Product Categories:
  • Glutamate receptor
  • pharmaceutical intermediates
Mol File:
100828-16-8.mol
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(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Chemical Properties

Boiling point:
546.7±60.0 °C(Predicted)
Density 
1.408±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at RT
solubility 
H2O: 99.2 mg/mL
form 
solid
pka
1.89±0.20(Predicted)
color 
white
Water Solubility 
Soluble to 100 mM in water
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-26-36
WGK Germany 
3

MSDS

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(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Usage And Synthesis

Uses

(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid is a compound with NMDA antagonistic activity.

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 5193, 1989 DOI: 10.1016/S0040-4039(01)93739-6

Biological Activity

Potent NMDA antagonist. See separate isomer (3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonicacid ).

Biochem/physiol Actions

Potent and selective NMDA glutamate receptor antagonist; anticonvulsant.

storage

Room temperature (desiccate)

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