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R-(-)-Fluoxetine hydrochloride

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R-(-)-Fluoxetine hydrochloride Basic information

Product Name:
R-(-)-Fluoxetine hydrochloride
Synonyms:
  • Unii-7C4D25st1t
  • (R)-N-Methyl-3-(4-trifluoroMethylphenoxy)-3-phenylpropylaMine Hydrochloride
  • (γR)-N-Methyl-γ-[4-(trifluoroMethyl)phenoxy]benzenepropanaMine Hydrochloride
  • Fluoxetine R-IsoMer HCl
  • (R)-3-[4(TRIFLUOROMETHYL)PHENOXY]-N-METHYL-3-PHENYLPROPAN-1-AMINE HYDROCHLORIDE
  • (R)-FLUOXETINE
  • R-(-)-FLUOXETINE HYDROCHLORIDE
  • (R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride
CAS:
114247-09-5
MF:
C17H19ClF3NO
MW:
345.79
Product Categories:
  • Biogenic Amine Transport Inhibitors
  • Biogenic Amine Transport InhibitorsObesity Research
  • Neurotransmission
  • Neurotransmission (Obesity)
  • Neurotransmitters
  • Chiral Reagents
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
114247-09-5.mol
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R-(-)-Fluoxetine hydrochloride Chemical Properties

Melting point:
126-129°C
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
H2O: 20 mg/mL, soluble
form 
solid
color 
white
Water Solubility 
H2O: soluble >10mg/mL
InChI
1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1
InChIKey
GIYXAJPCNFJEHY-PKLMIRHRSA-N
SMILES
Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2
CAS DataBase Reference
114247-09-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-38-41
Safety Statements 
26-39
WGK Germany 
3
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2

MSDS

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R-(-)-Fluoxetine hydrochloride Usage And Synthesis

Chemical Properties

White Solid

Uses

As a selective serotonin reuptake inhibitor (SSRI), R-(-)-Fluoxetine hydrochloride can be used as an antidepressant.

Definition

ChEBI: A hydrochloride obtained by reaction of (R)-fluoxetine with one equivalent of hydrochloric acid.

Biological Activity

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.', 'Selective serotonin reuptake inhibitor.

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