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Sodium prasterone sulfate

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Sodium prasterone sulfate Basic information

Product Name:
Sodium prasterone sulfate
Synonyms:
  • Dehydroepiandrosterone-3-sulfate Sodium Salt Sodium Dehydroisoandrosterone-3-sulfate
  • DHEA sulfate,sodiuM salt
  • Androst-5-en-17-one, 3-(sulfooxy)-, sodium salt, (3.beta.)-
  • Androst-5-en-17-one, 3.beta.-hydroxy-, hydrogen sulfate, sodium salt
  • sodium dehydroepiandrosterone-3-sulfate
  • sodium dehydroisoandrosterone-3-sulfate
  • SODIUM PRASTERONR SULFATE
  • Androst-5-en-17-one, 3-(sulfooxy)-, sodium salt, (3b)- (9CI)
CAS:
1099-87-2
MF:
C19H27NaO5S
MW:
390.47
EINECS:
214-152-2
Product Categories:
  • Chemical
  • Steroids.
  • 17-Ketosteroids
  • Biochemistry
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • pharmaceutical intermediate and chemical research
Mol File:
1099-87-2.mol
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Sodium prasterone sulfate Chemical Properties

Melting point:
148-149 °C (dec.)(lit.)
refractive index 
10 ° (C=4, MeOH)
Flash point:
9℃
storage temp. 
-20°C
solubility 
methanol: clear to hazy
form 
powder
color 
white to off-white
Merck 
14,2871
InChIKey
GFJWACFSUSFUOG-QGVZUKINNA-M
SMILES
[C@]12([H])CC[C@]3(C)C(CC[C@@]3([H])[C@]1([H])CC=C1C[C@@H](OS([O-])(=O)=O)CC[C@]21C)=O.[Na+] |&1:0,4,9,11,17,25,r|
CAS DataBase Reference
1099-87-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
F,C,T
Risk Statements 
11-34-39/23/24/25-23/24/25
Safety Statements 
16-26-36/37/39-45-36/37-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
RTECS 
BV8397400
Toxicity
dog,LD50,intravaginal,> 500mg/kg (500mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 444, 1998.

MSDS

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Sodium prasterone sulfate Usage And Synthesis

Description

Dehydroepiandrosterone sulfate (DHEAS) is a metabolite of dehydroepiandrosterone that is the major secretory product of adrenal glands and is the predominant circulating precursor for active steroid hormones in humans. For example, in the fetoplacental-maternal unit, DHEAS acts as the primary precursor for placental estrogen biosynthesis. A normal circulating concentration of DHEAS is ~10 μM in young adults and is dramatically increased in some adrenocortical disorders.

Chemical Properties

White to Off-White Solid

Uses

An active agent in the preparation of a pharmaceutical for the treatment of asthma or other respiratory diseases.

Definition

ChEBI: An organic sodium salt that is the monosodium salt of dehydroepiandrosterone sulfate.

Sodium prasterone sulfateSupplier

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