Chloroacetamide Chemical Properties

Melting point:

116-118 °C(lit.)

Boiling point:

224.5 °C

Density 

0.84

vapor pressure 

0.05 mm Hg ( 20 °C)

refractive index 

1.4480 (estimate)

Flash point:

170 °C

storage temp. 

Store below +30°C.

solubility 

methanol: soluble1g/10 mL

form 

Crystalline Powder

pka

14.69±0.40(Predicted)

color 

White

PH

3.8-4.1 (40g/l, H2O, 20℃)

Water Solubility 

Soluble in water(90g/L).

Merck 

14,2110

BRN 

878191

InChIKey

VXIVSQZSERGHQP-UHFFFAOYSA-N

LogP

-0.530

CAS DataBase Reference

79-07-2(CAS DataBase Reference)

NIST Chemistry Reference

Acetamide, 2-chloro-(79-07-2)

EPA Substance Registry System

Acetamide, 2-chloro- (79-07-2)

Safety Information

Hazard Codes 

T

Risk Statements 

25-43-62

Safety Statements 

22-36/37-45

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

2

RTECS 

AB5075000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29241900

Hazardous Substances Data

79-07-2(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 138 mg/kg LD50 dermal Rat > 2000 mg/kg

MSDS

• Language:English Provider:2-Chloroacetamide
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Chloroacetamide Usage And Synthesis

Description

Chloroacetamide is a preservative used in several applications such as in cutting metalwork fluids, in paints or in glues. It can induce contact dermatitis in hairdressers, or in shoemakers when used as a leather preservative.

Chemical Properties

white crystalline powder

Uses

2-Chloroacetamide is used as surface-active agent in home laundry, cleaning products & household formulated cleaners, other industrial uses, petroleum production, polymer processing.

Uses

preservative in cosmetic and pharmaceutical creams, shampoos, bath lotions, etc.; preservative in glues, cooling fluids.

Uses

A component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.

Flammability and Explosibility

Non flammable

Contact allergens

Chloroacetamide as a preservative is used in several applications as in cutting metalworking fluids, in paints or in glues. It can induce contact dermatitis in hairdressers or in shoemakers, being used as a leather preservative.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic Cland NOx. See also N-CHLOROACETAMIDE.

Purification Methods

Recrystallise the amide from acetone and dry it under vacuum over P2O5. [Beilstein 2 IV 490.]

Chloroacetamide(79-07-2)Related Product Information

• 2-Iodoacetamide
• DIACETAMIDE
• 2-Phenylacetamide
• N,N-Dimethylacetamide
• 2-Cyanoacetamide
• Thioacetamide
• Acetamide
• Acetaminophen
• Chloroacetyl chloride
• Difluorochloromethane
• 3,5-DICHLORO-2-PYRIDONE
• FLUOROACETAMIDE
• Dichloroacetamide
• 2,2,2-Trichloroacetamide
• CHLOROACETYL ISOCYANATE
• 5-Chlorouracil
• CHLOROACETYL-L-TYROSINE
• N-Methylolchloroacetamide