2-(4-Aminophenyl)ethylamine Chemical Properties

Melting point:

28-31 °C(lit.)

Boiling point:

103 °C0.3 mm Hg(lit.)

Density 

1.034 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.591(lit.)

Flash point:

>230 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Viscous Liquid

pka

10.32±0.10(Predicted)

color 

Clear light yellow to brown-yellow

Water Solubility 

Insoluble in water.

Sensitive 

Air Sensitive

BRN 

1099913

Stability:

Air Sensitive

CAS DataBase Reference

13472-00-9(CAS DataBase Reference)

NIST Chemistry Reference

2-(4-Aminophenyl)ethylamine(13472-00-9)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

34-20/21/22

Safety Statements 

26-36/37/39-45-27

RIDADR 

UN 3259 8/PG 2

WGK Germany 

3

F 

2-10

HazardClass 

8

PackingGroup 

III

HS Code 

29215900

MSDS

• Language:English Provider:2-(4-Aminophenyl)ethylamine
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2-(4-Aminophenyl)ethylamine Usage And Synthesis

Chemical Properties

clear light yellow to brown-yellow viscous liquid

Uses

4-(2-Aminoethyl)aniline has been used in chemical modification of silk fibroin to tailor the overall hydrophilicity and structure of silk. It has been used as reagent in polycondensation reactions.

Application

2-(4-Aminophenyl)ethylamine (APEA) is an important amine compound for the study of reductive amination with 3-deoxy-d-mannuronic acid (Kdo) and for the synthesis of new heat-resistant biopolyureas by fermentation techniques^[1-2].

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 5219, 1984 DOI: 10.1016/S0040-4039(01)81568-9

General Description

4-(2-Aminoethyl)aniline undergoes coupling with carbohydrates by reductive amination to yield modified carbohydrates.

References

[1] H D GRIMMECKE; H B. Studies on the reductive amination of 3-deoxy-D-manno-octulosonic acid (Kdo).[J]. Glycoconjugate Journal, 1998. DOI:10.1023/a:1006955508077.
[2] HAJIME MINAKAWA. Fermentative production of 2-(4-aminophenyl)ethylamine to synthesize a novel heat-resistant biopolyurea.[J]. Bioscience, Biotechnology, and Biochemistry, 2022. DOI:10.1093/bbb/zbac077.

2-(4-Aminophenyl)ethylamine(13472-00-9)Related Product Information

• Sulfanilamide
• Phenetidine
• 4-Aminobenzonitrile
• Aniline
• DL-ALPHA-METHYLBENZYLAMINE
• 4-Amino-benzenesulfonic acid monosodium salt
• 4-Aminobenzoic acid
• Sulfanilic acid
• METHYL 4-(4-AMINOPHENYL)BUTANOATE
• Ethylamine
• 4-Aminophenylacetonitrile
• 2-(4-AMINOPHENYL)ETHYL AMINE 2HCL
• p-Anisidine
• Methyl anthranilate
• L-1-Phenylethylamine
• 4-Aminophenylacetic acid
• D/L-AMPHETAMINE HYDROCHLORIDE
• Anthranilic acid