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6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone

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6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone Basic information

Product Name:
6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone
Synonyms:
  • 6,7-BIS(2-METHOXYETHOXY)QUINAZOLIN-4(1H)-ONE
  • Erlotinib LactaM IMpurity
  • 6,7-Bis(2-Methoxyethoxy)-3H-quinazolin-4-one
  • 6,7-bis-Methoxyethoxy-quinazolin-4-one
  • Erlotinib iMpurity E
  • ERLOTINIBINT-F
  • 6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone 6,7-BIS(2-METHOXYETHOXY)QUINAZOLIN-4(1H)-ONE
  • 6,7-bis(2-methoxyethoxy)-1H-quinazolin-4-one
CAS:
179688-29-0
MF:
C14H18N2O5
MW:
294.3
EINECS:
605-867-4
Product Categories:
  • Erlotinib INTERMEDIATES
  • intermidiate of Erlotinib hydrochloride
  • Erlotinib
  • Aromatics
  • Heterocycles
  • Intermediates
  • Aromatics Compounds
  • Intermediate of erlotinib hydrochloride
Mol File:
179688-29-0.mol
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6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone Chemical Properties

Melting point:
185-189°C
Boiling point:
467.8±55.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO: ≥10mg/mL
pka
1.35±0.20(Predicted)
form 
powder
color 
off-white to light tan
InChI
InChI=1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
InChIKey
PMQWTUWLIGJTQD-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(OCCOC)C(OCCOC)=C2)C(=O)NC=1
CAS DataBase Reference
179688-29-0(CAS DataBase Reference)
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Safety Information

WGK Germany 
3
HS Code 
2933.59.8000
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6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

An intermediate in the synthesis of Erlotinib (E625000).

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