8-METHYL-8-AZABICYCLO[3.2.1]OCTANE Chemical Properties

Boiling point:

167-169 °C (lit.)

Density 

0.931 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.477(lit.)

Flash point:

108 °F

form 

liquid

pka

11.57±0.20(Predicted)

Merck 

13,9847

InChI

1S/C8H15N/c1-9-7-3-2-4-8(9)6-5-7/h7-8H,2-6H2,1H3/t7-,8+

InChIKey

XLRPYZSEQKXZAA-OCAPTIKFSA-N

SMILES

CN1[C@H]2CCC[C@@H]1CC2

LogP

1.740 (est)

Safety Information

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

16-26-36

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

HazardClass 

3.2

PackingGroup 

III

Storage Class

3 - Flammable liquids

Hazard Classifications

Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3

MSDS

• Language:English Provider:SigmaAldrich

8-METHYL-8-AZABICYCLO[3.2.1]OCTANE Usage And Synthesis

Uses

Tropane (8-methyl-8-azabicyclo[3.2.1]-octane) is a bridged bicyclic N-containing compound. The 8-methyl-8-azabicyclo[3.2.1]-octane has a tropane ring system, which is an important substructure in a number of natural products and synthetic compounds of biological and medicinal importance. Production of tropane alkaloid in callus and root cultures of seven Hyoscyamus species has been studied. Tropane derivatives are reported to undergo rapid N-methyl inversion.

General Description

Tropane (8-methyl-8-azabicyclo[3.2.1]-octane) is a bridged bicyclic N-containing compound. The 8-methyl-8-azabicyclo[3.2.1]-octane has a tropane ring system, which is an important substructure in a number of natural products and synthetic compounds of biological and medicinal importance. Production of tropane alkaloid in callus and root cultures of seven Hyoscyamus species has been studied. Tropane derivatives are reported to undergo rapid N-methyl inversion.

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