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ADRENOCHROME

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ADRENOCHROME Basic information

Product Name:
ADRENOCHROME
Synonyms:
  • 2,3-dihydro-3-hydroxy-1-methyl-1h-indole-6-dione
  • 3-hydroxy-1-methyl-6-indolinedione
  • adraxone
  • D,L-Adrenochrome (3-Hydroxy-1-methyl-5,6-indolinedione
  • usafuctl-7
  • 2,3-DIHYDRO-3-HYDROXY-1-METHYL-1H-INDOLE-5,6-DIONE
  • 3-HYDROXY-1-METHYL-5,6-INDOLINE-DIONE
  • ADRENOCHROME
CAS:
54-06-8
MF:
C9H9NO3
MW:
179.17
EINECS:
200-192-8
Product Categories:
  • Aromatics
  • Heterocycles
  • Indoles and derivatives
  • Various Intermediates
  • Intermediates
  • 54-06-8
Mol File:
54-06-8.mol
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ADRENOCHROME Chemical Properties

Melting point:
115-120°C
Boiling point:
311.69°C (rough estimate)
Density 
1.2822 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
−20°C
solubility 
Methanol (Slightly), Water
pka
13.31±0.20(Predicted)
form 
Solid
color 
Red to Black
Stability:
Air Sensitive, Light Sensitive
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
NM1925000
HS Code 
29339980

MSDS

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ADRENOCHROME Usage And Synthesis

Chemical Properties

Red Crystalline Solid

Uses

The substance mainly responsible for the red colours produced during the mild oxidation of adrenaline

Uses

Adrenochrome is a derivative of epinephrine. When complexed with a salicylate, its stability is increased (carbazochrome). It was claimed to reduce blood loss, but the evidence is sparse.

Definition

ChEBI: Adrenochrome is a member of indoles.

Purification Methods

It was crystallised from MeOH/formic acid, as red crystals of the hemihydrate, and stored in a vacuum desiccator. The mono-semicarbazone (Carbazochrome) [69-81-8] M 236.2, crystallises as orange-red crystals from dilute EtOH with m ~203o (dec) and is haemostatic. [Heacock Chem Rev 59 181 1959, Beilstein 21 III/IV 6434.]

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