Choline salicylate
Choline salicylate Basic information
- Product Name:
- Choline salicylate
- Synonyms:
-
- Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-hydroxybenzoic acid (1:1)
- BASIONIC(R) FS 65, COL Salicylat
- salicol
- salicylicacid,ion(1-),choline
- salicylicacidcholinesalt
- satibon
- COL SALICYLAT
- COL SALICYLATE
- CAS:
- 2016-36-6
- MF:
- C12H19NO4
- MW:
- 241.28
- EINECS:
- 217-948-8
- Mol File:
- 2016-36-6.mol
Choline salicylate Chemical Properties
- Melting point:
- 49.5-50.0°
- Boiling point:
- 384.06°C (rough estimate)
- Density
- 1.1442 (rough estimate)
- refractive index
- 1.4596 (estimate)
- Flash point:
- 183 °C
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Colourless to Light Brown Oil
- Stability:
- Hygroscopic
- EPA Substance Registry System
- Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-hydroxybenzoic acid (1:1) (2016-36-6)
Safety Information
- WGK Germany
- 2
- RTECS
- GA6475000
- F
- 3-10
MSDS
- Language:English Provider:SigmaAldrich
Choline salicylate Usage And Synthesis
Description
Choline salicylate is absorbed more rapidly than aspirin and produces higher salicylate plasma levels. It is available as a mint-flavored liquid.
Originator
Arthropan ,Purdue , US,1959
Uses
Choline Salicylate displays protective effects in the treatment of Alzheimer’s disease. It has the potential to relieve pain associated with mouth ulcers.
Definition
ChEBI: Choline salicylate is a hydroxybenzoic acid. It is functionally related to a salicylic acid.
Manufacturing Process
A method of preparation is to react an acid salt of choline (such as choline chloride or choline bromide) with an alkaline salt of salicylic acid (such as sodium salicylate, potassium salicylate, or magnesium salicylate) in an alcoholic media.
brand name
Arthropan (Purdue Frederick).
Therapeutic Function
Analgesic; Antipyretic
Clinical Use
Choline salicylate has a lower incidence of GI side effects compared with aspirin, and it has been shown to be particularly useful in treating juvenile rheumatoid arthritis, in which aspirin was ineffective.
Choline salicylateSupplier
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Choline salicylate(2016-36-6)Related Product Information
- Hydroxyethyl Cellulose
- Methyl salicylate
- Acetylsalicylic acid
- AMMONIUM SALICYLATE
- Hydroxyethyl starch
- Sodium salicylate
- Sodium isethionate
- Choline hydroxide
- 2-(2-Aminoethylamino)ethanol
- Tetraethylammonium hydroxide
- Choline chloride
- 5-Sulfosalicylic acid dihydrate
- Tetraethylammonium bromide
- Methyl 2-hydroxyethyl cellulose
- 2-(METHYLSULFONYL)ETHANOL
- Salicylic acid
- ALLOPHYCOCYANIN
- BEPHENIUM HYDROXYNAPHTHOATE