2,3-Diaminopyridine Chemical Properties

Melting point:

110-115 °C (lit.)

Boiling point:

195°C 55mm

Density 

1.1118 (rough estimate)

refractive index 

1.5340 (estimate)

Flash point:

205 °C

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

H2O: soluble50mg/mL, opaque (brown to very dark brown)

form 

Solid

pka

6.78±0.36(Predicted)

color 

Very Dark Brown

Water Solubility 

100 g/L (20 ºC)

Sensitive 

Air Sensitive

BRN 

109869

InChIKey

ZZYXNRREDYWPLN-UHFFFAOYSA-N

CAS DataBase Reference

452-58-4(CAS DataBase Reference)

NIST Chemistry Reference

2,3-Pyridinediamine(452-58-4)

Safety Information

Hazard Codes 

Xn,Xi,T

Risk Statements 

22-36/37/38-25

Safety Statements 

26-36/37-45-37/39-28A-36

RIDADR 

UN 2811

WGK Germany 

3

RTECS 

US7548000

F 

9

Hazard Note 

Irritant

HazardClass 

6.1

PackingGroup 

II

HS Code 

29333999

MSDS

• Language:English Provider:Pyridine-2,3-diamine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,3-Diaminopyridine Usage And Synthesis

Chemical Properties

Brown powder

Uses

2,3-Diaminopyridine was used in the synthesis of 2,3-diaminopyridinium-4-hydroxybenzoate1. It was used as internal standard in analysis of poly(amidoamine)dendrimers having different terminal functionalities by capillary electrophoresis. It was used as reagent in synthesis of imidazopyridines and organometallic complexes.

Application

2,3-diaminopyridine is as intermediates for making a variety of pharmaceutically important compounds, such as it is useful in the production of imidazole pyridine inotropic agents.

General Description

2,3-Diaminopyridine forms the bis-condensed Schiff base with salicylaldehyde. It forms charge transfer complex with tetrachloro-p-benzoquinone and tetracyanoethylene.

Synthesis

2,3-Diaminopyridine has been prepared by reduction of 2-amino-3-nitropyridine with iron and aqueous acidified ethanol, tin and hydrochloric acid.

Purification Methods

It crystallises from *benzene and sublimes in vacuo. [Beilstein 22/11 V 241.]

2,3-Diaminopyridine(452-58-4)Related Product Information

• Iminodiacetonitrile
• 2-Aminopyridine
• 3,4-Diaminopyridine
• PYRIDINE-2,4-DIAMINE
• 4-Dimethylaminopyridine
• Pyridine
• 4-Aminopyridine
• 3-Aminopyridine
• 2,5-Diaminopyridine
• HYDRAZINE
• 2,6-Diaminopyridine
• Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
• 2-Amino-3-nitro-6-picoline
• 2-AMINO-6-CHLORO-3-NITROPYRIDINE
• Pirenzepine
• 2-Amino-3-nitro-4-picoline
• Phenazopyridine hydrochloride
• 2-Nitro-3-pyridinamine