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Methyl 4-aminopyridine-2-carboxylate

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Methyl 4-aminopyridine-2-carboxylate Basic information

Product Name:
Methyl 4-aminopyridine-2-carboxylate
Synonyms:
  • 4-AMINO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
  • 2-Pyridinecarboxylicacid,4-amino-,methylester(9CI)
  • CHEMPACIFIC 38133
  • METHYL 4-AMINO-PYRIDINE-2-CARBOXYLATE
  • METHYL 4-AMINO-PYRIDINE-2-CARBOXYLIC ACID
  • Methyl 4-amino-2-pyridinecarboxylate
  • methyl 4-aminopicolinate
  • 4-Amino-2-pyridine carboxylic acid methyl ester
CAS:
71469-93-7
MF:
C7H8N2O2
MW:
152.15
Product Categories:
  • Pyridine series
  • CARBOXYLICESTER
  • GLYCINESCAFFOLD
  • Pyridines
  • Heterocycle-Pyridine series
  • VX-548
Mol File:
71469-93-7.mol
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Methyl 4-aminopyridine-2-carboxylate Chemical Properties

Melting point:
129-130°
Boiling point:
333.7±22.0 °C(Predicted)
Density 
1.238±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
4.35±0.10(Predicted)
color 
White to Light yellow
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Safety Information

RIDADR 
UN2811
HazardClass 
IRRITANT
HS Code 
2933399990
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Methyl 4-aminopyridine-2-carboxylate Usage And Synthesis

Chemical Properties

Off-white solid

Uses

Methyl 4-aminopyridine-2-carboxylate is an organic reagent, mostly used in chemical manufacturing and scientific experimental research.

Synthesis

Methyl 4-aminopyridine-2-carboxylate is synthesised using Methyl 4-azidopyridine-2-carboxylate as a raw material by chemical reaction. The specific synthesis steps are as follows:
4-Azido-pyridine-2-carboxylic acid methyl ester (3.9 g, 22 mmol, 1 eq) was solubilized in methanol (50 mL) and palladium 10 percent w on carbon (400 mg) was added. The mixture was stirred at room temperature over 4 bars pressure of hydrogen until completion of the reaction. The mixture was then filtered over a short pad of celite, and rinsed with methanol to afford the expected compound as a yellow powder (3.0 g, 90percent yield).

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