Methyl 4-aminopyridine-2-carboxylate
Methyl 4-aminopyridine-2-carboxylate Basic information
- Product Name:
- Methyl 4-aminopyridine-2-carboxylate
- Synonyms:
-
- 4-AMINO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
- 2-Pyridinecarboxylicacid,4-amino-,methylester(9CI)
- CHEMPACIFIC 38133
- METHYL 4-AMINO-PYRIDINE-2-CARBOXYLATE
- METHYL 4-AMINO-PYRIDINE-2-CARBOXYLIC ACID
- Methyl 4-amino-2-pyridinecarboxylate
- methyl 4-aminopicolinate
- 4-Amino-2-pyridine carboxylic acid methyl ester
- CAS:
- 71469-93-7
- MF:
- C7H8N2O2
- MW:
- 152.15
- Product Categories:
-
- Pyridine series
- CARBOXYLICESTER
- GLYCINESCAFFOLD
- Pyridines
- Heterocycle-Pyridine series
- VX-548
- Mol File:
- 71469-93-7.mol
Methyl 4-aminopyridine-2-carboxylate Chemical Properties
- Melting point:
- 129-130°
- Boiling point:
- 333.7±22.0 °C(Predicted)
- Density
- 1.238±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 4.35±0.10(Predicted)
- color
- White to Light yellow
Methyl 4-aminopyridine-2-carboxylate Usage And Synthesis
Chemical Properties
Off-white solid
Uses
Methyl 4-aminopyridine-2-carboxylate is an organic reagent, mostly used in chemical manufacturing and scientific experimental research.
Synthesis
Methyl 4-aminopyridine-2-carboxylate is synthesised using Methyl 4-azidopyridine-2-carboxylate as a raw material by chemical reaction. The specific synthesis steps are as follows:
4-Azido-pyridine-2-carboxylic acid methyl ester (3.9 g, 22 mmol, 1 eq) was solubilized in methanol (50 mL) and palladium 10 percent w on carbon (400 mg) was added. The mixture was stirred at room temperature over 4 bars pressure of hydrogen until completion of the reaction. The mixture was then filtered over a short pad of celite, and rinsed with methanol to afford the expected compound as a yellow powder (3.0 g, 90percent yield).
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