(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Chemical Properties

Melting point:

97-101 °C

alpha 

-38 º (c=1, MeOH)

Boiling point:

300.3±42.0 °C(Predicted)

Density 

1.092±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

powder to crystal

pka

14.93±0.10(Predicted)

color 

White to Almost white

InChI

InChI=1S/C13H18FNO/c1-15-7-6-13(11(8-15)9-16)10-2-4-12(14)5-3-10/h2-5,11,13,16H,6-9H2,1H3/t11-,13-/m0/s1

InChIKey

CXRHUYYZISIIMT-AAEUAGOBSA-N

SMILES

N1(C)CC[C@@H](C2=CC=C(F)C=C2)[C@H](CO)C1

CAS DataBase Reference

105812-81-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

N-Xn,N,Xn

Risk Statements 

51/53-41-22

Safety Statements 

61-39-26-22-37/39-24

RIDADR 

UN3077

HazardClass 

9

PackingGroup 

III

HS Code 

29333999

MSDS

• Language:English Provider:ACROS

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

An intermediate in the synthesis of Paroxetine, a selective serotonin reuptake inhibitor.

Uses

An intermediate in the synthesis of Paroxetine (P205750), a selective serotonin reuptake inhibitor.

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine(105812-81-5)Related Product Information

• 2,2,6,6-Tetramethyl-4-piperidinol
• DROPERIDOL
• Haloperidol
• 1,2,2,6,6-Pentamethyl-4-piperidinol
• Tris(hydroxymethyl)nitromethane
• Triacetonediamine
• 4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine
• paroxetine Mesylate
• Paroxetine Impurity 5
• Paroxetine Related Impurity 7 3S4R
• 3S,4R-4-[phenyl-1-methylpiperidinyl] methanol
• 1,3-Benzodioxol-4-ol
• Paroxetine Impurity 16
• PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE)
• Paroxetine Impurity 17
• 1,3-Benzodioxole
• Paroxetine EP Impurity I HCl 3S4R
• Paroxetine