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9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID

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9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID Basic information

Product Name:
9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID
Synonyms:
  • 5-hydroxy-2-(3-hydroxy-1-octenyl)-3-oxo-cyclopentaneheptanoicaci
  • 5-hydroxy-2-(3-hydroxy-1-octenyl)-3-oxocyclopentaneheptanoicacid
  • 9,15-dihydroxy-11-oxo-,(9-alpha,13e,15s)-prost-13-en-1-oicaci
  • pgd1
  • PROSTAGLANDIN D1
  • 7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]heptanoic acid
  • (13E,15S)-9α,15-Dihydroxy-11-oxoprost-13-en-1-oic acid
  • 11-DehydroPGF1α
CAS:
17968-82-0
MF:
C20H34O5
MW:
354.48
Mol File:
17968-82-0.mol
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9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID Chemical Properties

Melting point:
64.5-65.5 °C
Boiling point:
544.6±50.0 °C(Predicted)
Density 
1.131±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >5 mg/ml (from PGD2)
pka
4.78±0.10(Predicted)
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9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACID Usage And Synthesis

Description

Prostaglandin D1 (PGD1) is the 1-series analog of PGD2 . It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2.

Uses

Prostaglandin D1 is used in pharmalogical and in functional characterization of novel EP & DP receptor agonist: DPI receptor mediates penile erection in multiple species.

Definition

ChEBI: Prostaglandin D1 is a prostaglandins D. It has a role as a human metabolite. It is a conjugate acid of a prostaglandin D1(1-).

9ALPHA,15S-DIHYDROXY-11-OXO-PROST-13E-EN-1-OIC ACIDSupplier

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