2-(Phenylsulfonyl)aniline Chemical Properties

Melting point:

120-122 °C(lit.)

Boiling point:

439.6±28.0 °C(Predicted)

Density 

1.295±0.06 g/cm3(Predicted)

pka

-1.06±0.10(Predicted)

form 

solid

color 

Pale yellow

CAS DataBase Reference

4273-98-7(CAS DataBase Reference)

EPA Substance Registry System

o-Aminodiphenyl sulfone (4273-98-7)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36/37/38-22

Safety Statements 

36/37/39-26

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29214200

MSDS

• Language:English Provider:2-Aminophenyl phenyl sulfone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

2-(Phenylsulfonyl)aniline Usage And Synthesis

Chemical Properties

off-white to beige powder

Uses

2-(Phenylsulfonyl)aniline may be used in chemical synthesis.

Preparation

Preparation?of?the?chromophore : Will 1-(2-Nitrophenylsulfonyl)benzene?restored.

Synthesis

General procedure for the synthesis of 2-aminodiphenyl sulfone from 2-nitrodiphenyl sulfone: 5.22 g (0.09315 mol) of iron powder was added in batches to a 60 mL suspension of acetic acid containing 4.9 g (0.01863 mol) of 2-nitrodiphenyl sulfone. The reaction mixture was stirred at 70°C for 3 hours, followed by cooling and filtration to remove inorganic impurities. To the filtrate was added 100 mL of water, and the precipitate precipitated was filtered, washed with water, and dried under vacuum to give 4 g (92% yield) of 2-(phenylsulfonyl)aniline (10f). The product was analyzed by mass spectrometry (LS MC m/z 234 (M + 1)) and 1H NMR (DMSO-d6, 400 MHz) δ 7.91 (d, J = 8Hz, 2H), 7.67 (t, J = 9.6Hz, 2H), 7.58 (t, J = 7.6Hz, 2H), 7.29 (t, J = 7.2Hz, 1H), 6.77 (d, J = 8.4 Hz, 1H), 6.67 (t, J = 7.6 Hz, 1H), 6.12 (s, 2H) confirmed.

Properties and Applications

the fastness properties in cotton:

References

[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 15, p. 4614 - 4627
[2] Helvetica Chimica Acta, 1980, vol. 63, # 6, p. 1412 - 1419
[3] Journal of the American Chemical Society, 1950, vol. 72, p. 965,969
[4] Journal of the Chemical Society, 1938, p. 899,902
[5] Chemische Berichte, 1901, vol. 34, p. 1155

2-(Phenylsulfonyl)aniline(4273-98-7)Related Product Information

• 4,4'-Methylenedianiline
• Acid Blue 93
• p-Anisidine
• Aniline
• 4,4'-Diaminodiphenylsulfone
• Diphenyl sulfone
• 4-Aminobenzoic acid
• Tetradifon
• Sulfanilic acid
• PHENYL VALERATE
• PHENYL RESIN
• Anthranilic acid
• DIOXOPROMETHAZINE HCL
• 2-Nitrophenyl phenyl sulfone
• 4-CHLORO-2-NITRO-1-(PHENYLSULFONYL)BENZENE
• Phenylacetic acid
• OXOMEMAZINE
• 2-Aminobiphenyl