Basic information Safety Supplier Related

1,2,3-BENZOTRIAZIN-4(3H)-ONE

Basic information Safety Supplier Related

1,2,3-BENZOTRIAZIN-4(3H)-ONE Basic information

Product Name:
1,2,3-BENZOTRIAZIN-4(3H)-ONE
Synonyms:
  • 1,2,3-Benzotriazin-4(3H)-one 98%
  • 1,2,3-benzotriazin-4-(1h)-one
  • 1,2,3-benzotriazin-4(1h)-one
  • 1,2,3-Benzotriazin-4-ol
  • 1,2,3-benzotriazin-4-one
  • 3H-1,2,3-Benzotriazin-4-one
  • 4-keto-(3h)-1,2,3-benzotriazine
  • 4-Ketobenz-1,2,3-triazine
CAS:
90-16-4
MF:
C7H5N3O
MW:
147.13
EINECS:
201-971-5
Product Categories:
  • pharmacetical
  • Heterocyclic Compounds
  • Building Blocks
  • Heterocyclic Building Blocks
  • Triazines
Mol File:
90-16-4.mol
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1,2,3-BENZOTRIAZIN-4(3H)-ONE Chemical Properties

Melting point:
216-218 °C (lit.)
Boiling point:
282℃
Density 
1.47
refractive index 
1.5500 (estimate)
Flash point:
125℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in most organic solvents.
form 
Solid
pka
-4.67±0.20(Predicted)
color 
Needles from cyclohexane
BRN 
124996
InChIKey
DMSSTTLDFWKBSX-UHFFFAOYSA-N
CAS DataBase Reference
90-16-4(CAS DataBase Reference)
EPA Substance Registry System
1,2,3-Benzotriazin-4(1H)-one (90-16-4)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
RTECS 
DM0800000
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
2933698090
Hazardous Substances Data
90-16-4(Hazardous Substances Data)
Toxicity
LD50 ipr-mus: 50 mg/kg NTIS** AD277-689

MSDS

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1,2,3-BENZOTRIAZIN-4(3H)-ONE Usage And Synthesis

Chemical Properties

Tan powder. Soluble in alkaline solutions and organic bases.

Uses

Organic synthesis.

Uses

1,2,3-Benzotriazin-4(3H)one is used to prepare 3-methoxymethyl-3H-benzo[d][1,2,3]triazin-4-one by reacting with dimethoxymethane. Further, it undergoes thermal condensation with alfa-amino acids to give 3H-1,4-benzodiazepin-(1H,4H)-2,5-diones. In addition to this, it is employed as a reagent to synthesize 1,2,3-bBenzotriazin-4-one-arylpiperazine derivatives.

Uses

1,2,3-Benzotriazin-4(3H)-one is part of a group of compounds that exhibit antimicrobial activity. 1,2,3-Benzotriazin-4(3H)-one is also used as a reagent to synthesize 1,2,3-Benzotriazin-4-one-arylpiperazine derivatives, compounds that act as Serotonin (HCl: S274980) receptor ligands.

Definition

Bicyclic.

General Description

1,2,3-Benzotriazin-4(3H)-one is an 1,2,3-benzotriazine derivative. 1,2,3-Benzotriazin-4(3H)-one undergoes thermal condensation with α-amino acids to yield 3H-1,4-benzodiazepin-(1H,4H)-2,5-diones. 1,2,3-benzotriazin-4(3H)-one on thermolysis yields quinazolino[3,2-c][1,2,3]benzotriazin-8-one.

Safety Profile

Poison by intraperitoneal route.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of NOx.

1,2,3-BENZOTRIAZIN-4(3H)-ONESupplier

Guizhou Yituo Chemical Technology Co., Ltd Gold
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18628235590
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wuliming@yituochem.cn
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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Alfa Aesar
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400-6106006
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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Sales-CN@TCIchemicals.com