1,2,3-BENZOTRIAZIN-4(3H)-ONE
1,2,3-BENZOTRIAZIN-4(3H)-ONE Basic information
- Product Name:
- 1,2,3-BENZOTRIAZIN-4(3H)-ONE
- Synonyms:
-
- 1,2,3-Benzotriazin-4(3H)-one 98%
- 1,2,3-benzotriazin-4-(1h)-one
- 1,2,3-benzotriazin-4(1h)-one
- 1,2,3-Benzotriazin-4-ol
- 1,2,3-benzotriazin-4-one
- 3H-1,2,3-Benzotriazin-4-one
- 4-keto-(3h)-1,2,3-benzotriazine
- 4-Ketobenz-1,2,3-triazine
- CAS:
- 90-16-4
- MF:
- C7H5N3O
- MW:
- 147.13
- EINECS:
- 201-971-5
- Product Categories:
-
- pharmacetical
- Heterocyclic Compounds
- Building Blocks
- Heterocyclic Building Blocks
- Triazines
- Mol File:
- 90-16-4.mol
1,2,3-BENZOTRIAZIN-4(3H)-ONE Chemical Properties
- Melting point:
- 216-218 °C (lit.)
- Boiling point:
- 282℃
- Density
- 1.47
- refractive index
- 1.5500 (estimate)
- Flash point:
- 125℃
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in most organic solvents.
- pka
- -4.67±0.20(Predicted)
- form
- Solid
- color
- Needles from cyclohexane
- BRN
- 124996
- InChIKey
- DMSSTTLDFWKBSX-UHFFFAOYSA-N
- CAS DataBase Reference
- 90-16-4(CAS DataBase Reference)
- EPA Substance Registry System
- 1,2,3-Benzotriazin-4(1H)-one (90-16-4)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39
- WGK Germany
- 3
- RTECS
- DM0800000
- TSCA
- Yes
- HazardClass
- IRRITANT
- HS Code
- 2933698090
- Hazardous Substances Data
- 90-16-4(Hazardous Substances Data)
- Toxicity
- LD50 ipr-mus: 50 mg/kg NTIS** AD277-689
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
1,2,3-BENZOTRIAZIN-4(3H)-ONE Usage And Synthesis
Chemical Properties
Tan powder. Soluble in alkaline solutions and organic bases.
Uses
Organic synthesis.
Uses
1,2,3-Benzotriazin-4(3H)one is used to prepare 3-methoxymethyl-3H-benzo[d][1,2,3]triazin-4-one by reacting with dimethoxymethane. Further, it undergoes thermal condensation with alfa-amino acids to give 3H-1,4-benzodiazepin-(1H,4H)-2,5-diones. In addition to this, it is employed as a reagent to synthesize 1,2,3-bBenzotriazin-4-one-arylpiperazine derivatives.
Uses
1,2,3-Benzotriazin-4(3H)-one is part of a group of compounds that exhibit antimicrobial activity. 1,2,3-Benzotriazin-4(3H)-one is also used as a reagent to synthesize 1,2,3-Benzotriazin-4-one-arylpiperazine derivatives, compounds that act as Serotonin (HCl: S274980) receptor ligands.
Definition
Bicyclic.
General Description
1,2,3-Benzotriazin-4(3H)-one is an 1,2,3-benzotriazine derivative. 1,2,3-Benzotriazin-4(3H)-one undergoes thermal condensation with α-amino acids to yield 3H-1,4-benzodiazepin-(1H,4H)-2,5-diones. 1,2,3-benzotriazin-4(3H)-one on thermolysis yields quinazolino[3,2-c][1,2,3]benzotriazin-8-one.
Safety Profile
Poison by intraperitoneal route.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of NOx.
1,2,3-BENZOTRIAZIN-4(3H)-ONESupplier
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1,2,3-BENZOTRIAZIN-4(3H)-ONE(90-16-4)Related Product Information
- Fmoc-O-tert-Butyl-L-serine 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl ester
- DEPBT
- 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one
- AZINPHOS-ETHYL
- AZINPHOS-METHYL
- 1,2,3-BENZOTRIAZIN-4(3H)-ONE
- N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate
- Razinodil
- FMOC-THR(TBU)-ODHBT
- 3-(hydroxymethyl)-4-ketobenz-1,2,3-triazine
- Fmoc-Glu(OBut)-ODhbt
- Fmoc-Gly-ODhbt
- AZINPHOS-METHYL OXON
- Fmoc-Asp(OBut)-ODhbt
- 1,2,3-BENZOTRIAZIN-4(3H)-ONE, 6-BROMO-
- Molinazone
- 3-(4-BROMOBENZYL)-1,2,3-BENZOTRIAZIN-4(3H)-ONE
- 3-(1-Phenyl-1H-pyrazol-5-yl)-1,2,3-benzotriazin-4(3H)-one