8-AZAGUANINE Chemical Properties

Melting point:

>300 °C(lit.)

Boiling point:

274.55°C (rough estimate)

Density 

1.5579 (rough estimate)

refractive index 

2.3000 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility 

DMSO (Slightly)

pka

6.75±0.20(Predicted)

form 

lyophilized powder

color 

White to yellow

Merck 

896

InChIKey

LPXQRXLUHJKZIE-UHFFFAOYSA-N

CAS DataBase Reference

134-58-7(CAS DataBase Reference)

NIST Chemistry Reference

8-Azaguanine(134-58-7)

EPA Substance Registry System

8-Azaguanine (134-58-7)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

XZ6157000

F 

10-23

HS Code 

29335990

Toxicity

LD50 oral in mouse: 1500mg/kg

MSDS

• Language:English Provider:SigmaAldrich

8-AZAGUANINE Usage And Synthesis

Chemical Properties

yellow powder

Uses

Antineoplastic;Purine antimetabolite

Uses

8-Azaguanine, is a purine analogue which shows antineoplastic activity.

Definition

ChEBI: A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.

Hazard

Mitotoic poison.

Purification Methods

Dissolve it in hot M NH4OH, filter, and cool. Recrystallise it, and wash it with water, then dry it in a vacuum. [Beilstein 26 III/IV 4171.]

8-AZAGUANINE(134-58-7)Related Product Information

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• 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE