Basic information Safety Supplier Related

NF449

Basic information Safety Supplier Related

NF449 Basic information

Product Name:
NF449
Synonyms:
  • 4,4',4'',4'''-[CARBONYLBIS(IMINO-5,1,3-BENZENETRIYL-BIS(CARBONYLIMINO))]TETRAKIS-1,3-BENZENEDISULFONIC ACID, OCTASODIUM SALT
  • 4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYL-IMINO)]]TETRAKIS(BENZENE-1,3-DISULFONIC ACID) OCTASODIUM SALT
  • 4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYLIMINO)]]TETRAKIS-(BENZENE-1,3-DISULFONIC ACID, 8NA)
  • NF449
  • NF449 OCTASODIUM SALT
  • 4,4',4'',4'''-(Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino)))tetrakis-1,3-benzenedisulfonicacid,octasodium
  • 4,4μ,4,4μ-[Carbonylbis[imino-5,1,3-benzenetriyl bis(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid) octasodium salt
  • NF449 - CAS 389142-38-5 - Calbiochem
CAS:
389142-38-5
MF:
C41H24N6Na8O29S8
MW:
1505.09
Product Categories:
  • Purinergics P2 receptor
Mol File:
389142-38-5.mol
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NF449 Chemical Properties

storage temp. 
2-8°C
solubility 
H2O: soluble
form 
solid
color 
white
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Safety Information

WGK Germany 
3

MSDS

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NF449 Usage And Synthesis

Biological Activity

Potent purinergic receptor antagonist that displays high selectivity for P2X 1 (IC 50 values are 0.28, 0.69, 120, 1820, 47000 and > 300000 nM for rP2X 1 , rP2X 1+5 , rP2X 2+3 , rP2X 3 , rP2X 2 and P2X 4 receptors respectively). Provides antithrombotic protection in vivo . Also acts as a G s α -selective antagonist.

NF449Supplier

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