Basic information Safety Supplier Related

NF449

Basic information Safety Supplier Related

NF449 Basic information

Product Name:
NF449
Synonyms:
  • 4,4',4'',4'''-[CARBONYLBIS(IMINO-5,1,3-BENZENETRIYL-BIS(CARBONYLIMINO))]TETRAKIS-1,3-BENZENEDISULFONIC ACID, OCTASODIUM SALT
  • 4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYL-IMINO)]]TETRAKIS(BENZENE-1,3-DISULFONIC ACID) OCTASODIUM SALT
  • 4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYLIMINO)]]TETRAKIS-(BENZENE-1,3-DISULFONIC ACID, 8NA)
  • NF449
  • NF449 OCTASODIUM SALT
  • 4,4',4'',4'''-(Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino)))tetrakis-1,3-benzenedisulfonicacid,octasodium
  • 4,4μ,4,4μ-[Carbonylbis[imino-5,1,3-benzenetriyl bis(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid) octasodium salt
  • NF449 - CAS 389142-38-5 - Calbiochem
CAS:
389142-38-5
MF:
C41H32N6O29S8
MW:
1329.24
Product Categories:
  • Purinergics P2 receptor
Mol File:
389142-38-5.mol
More
Less

NF449 Chemical Properties

Melting point:
>300°C
Density 
1.991±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: soluble
form 
solid
pka
-2.03±0.50(Predicted)
color 
white
Stability:
Hygroscopic
More
Less

Safety Information

WGK Germany 
3

MSDS

More
Less

NF449 Usage And Synthesis

Uses

NF449 is a known P2X1 receptor antagonist used to regulate the intravascular platelet aggregation commonly seen in systematic thromboembolism.

Biological Activity

Potent purinergic receptor antagonist that displays high selectivity for P2X 1 (IC 50 values are 0.28, 0.69, 120, 1820, 47000 and > 300000 nM for rP2X 1 , rP2X 1+5 , rP2X 2+3 , rP2X 3 , rP2X 2 and P2X 4 receptors respectively). Provides antithrombotic protection in vivo . Also acts as a G s α -selective antagonist.

NF449Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
EMMX Biotechnology LLC
Tel
888-539-0666
Email
info@emmx.com
Chunchuang (Wuhan) Technology Co., Ltd
Tel
15342225168
Email
yutianchun2007@126.com
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com