Basic information Safety Supplier Related

N-Acetyl-D-galactosamine

Basic information Safety Supplier Related

N-Acetyl-D-galactosamine Basic information

Product Name:
N-Acetyl-D-galactosamine
Synonyms:
  • 2-Acetamido-2-deoxy-D-galactopyranose N-Acetyl-D-chondrosamine
  • N-((3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-3-yl)acetaMide
  • 2-(acetylamino)-2-deoxy-alpha-d-galactopyranos
  • N-[(2S,3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
  • 2-(Acetylamino)-2-deoxy-α-D-galactopyranose
  • 2-Acetylamino-2-deoxy-α-D-galactopyranose
  • N-Acetyl-D-galactosamine,97%
  • N-((3R,4R,5R)-3,4,5,6-Tetrahydroxy-1-oxohexan-2-yl)acetamide
CAS:
14215-68-0
MF:
C8H15NO6
MW:
221.21
EINECS:
217-321-9
Product Categories:
  • Aminosugars
  • Biochemistry
  • Galactose
  • Sugars
  • Dextrins、Sugar & Carbohydrates
Mol File:
14215-68-0.mol
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N-Acetyl-D-galactosamine Chemical Properties

Melting point:
158-162 °C
alpha 
85 º (c=1, H2O, 5 hrs)
Boiling point:
362.26°C (rough estimate)
Density 
1.3572 (rough estimate)
refractive index 
85 ° (C=1, H2O)
storage temp. 
Sealed in dry,2-8°C
solubility 
Methanol (Slightly, Sonicated), Water (Slightly)
form 
Solid
pka
12.04±0.70(Predicted)
color 
White to Off-White
optical activity
+115 → +80
Water Solubility 
almost transparency
Concentration
0.1 mCi/ml
Solvent
Ethanol:water (7:3)
Specific Activity
40-60 mCi/mmol
InChIKey
OVRNDRQMDRJTHS-KEWYIRBNSA-N
CAS DataBase Reference
14215-68-0(CAS DataBase Reference)
EPA Substance Registry System
.alpha.-D-Galactopyranose, 2-(acetylamino)-2-deoxy- (14215-68-0)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
22-24/25
WGK Germany 
3
3-10
HS Code 
29329990

MSDS

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N-Acetyl-D-galactosamine Usage And Synthesis

Chemical Properties

white to off-white fine crystalline powder

Uses

N-Acetyl-D-galactosamine is a bio-activated reporters to visualize.

Definition

ChEBI: N-acetyl-D-galactosamine is the D-enantiomer of N-acetylgalactosamine. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a N-acetyl-D-hexosamine and a N-acetylgalactosamine.

Enzyme inhibitor

This acetylated aminosugar (FW = 221.21 g/mol), also known as 2acetamido-2-deoxy-D-galactopyranose and abbreviated D-GalpNAc and NAGA, is a component of many glycoproteins, chondroitin, and bloodgroup substances. N-Acetyl-D-galactosamine will also inhibit the binding of ligands to many lectins. Target(s): b-N-acetylhexosaminidase; a-N-acetylgalactosaminidase; discoidins I and II, or Dictyostelium discoideum agglutinins; Bauhinia purpurea agglutinin; lima bean (Phaseolus lunatus) lectin; Wistaria floribunda phytomitogen; horse gram (Dolichos biflorus) lectin; Sophora japonica hemagglutinin; soybean (Glycine max) agglutinin; snail (Helix pomatia) hemagglutinin; a-galactosidase B; b-N-acetylglucosaminidase; b-N-acetylgalactosaminidase; galactose oxidase, also alternative substrate; keratan sulfotransferase, weakly inhibited; aralin; rRNA N-glycosylase; peptidoglycan b-N-acetylmuramidase; polypeptide N acetylgalactosaminyltransferase.

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