D(+)-10-Camphorsulfonyl chloride Chemical Properties

Melting point:

67-68 °C

alpha 

33 º (c=1, CHCl3 22 ºC)

Boiling point:

349.4±15.0 °C(Predicted)

Density 

1.2078 (estimate)

refractive index 

32 ° (C=1, CHCl3)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Crystalline Powder

color 

Off-white to beige

optical activity

[α]22/D +33°, c = 1 in chloroform

Sensitive 

Moisture Sensitive

BRN 

3205974

InChIKey

BGABKEVTHIJBIW-UHFFFAOYSA-N

CAS DataBase Reference

21286-54-4(CAS DataBase Reference)

NIST Chemistry Reference

(+)-Camphor-10-sulfonyl chloride(21286-54-4)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

10-21

HazardClass 

8

PackingGroup 

II

HS Code 

29147000

MSDS

• Language:English Provider:(1S)-Camphor-10-sulfonic acid chloride
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

D(+)-10-Camphorsulfonyl chloride Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

A chiral derivative of Camphor.

Uses

As a useful synthetic intermediate, D(+)-10-Camphorsulfonyl chloride can be used for asymmetric hydroxylation

Purification Methods

If free from OH bands in the IR, then recrystallise it from Et2O or pet ether; otherwise treat it with SOCl2 at 50o for 30minutes, evaporate, dry the residue over KOH in a vacuum and recrystallise it. The (±)-acid chloride has m 85o [Bartlett & Knox Org Synth 45 14 1965]. Itis characterised as the amide (prisms from EtOH) m 132o, [ ] 17 (+) and (-) 1.5o (EtOH). On repeated recrystallisation from EtOH the anilide has m 120.5-121o, [] 25 +76o (c 1, CHCl3). [Read & Storey J Chem Soc 2761 1930, Sutherland & Shriner J Am Chem Soc 58 62 1936, Halterman et al. J Am Chem Soc 109 8105 1987, Bartlet & Knox Org Synth 45 55 1945, Beilstein 11 IV 650.]

D(+)-10-Camphorsulfonyl chloride(21286-54-4)Related Product Information

• 4-Nitrobenzenesulfonyl chloride
• N-Acetylsulfanilyl chloride
• D-CAMPHOR
• Sodium chloride
• Benzenesulfonyl chloride
• Zinc chloride
• Potassium chloride
• Camphor
• Oxalyl chloride
• Choline chloride
• Ethanesulfonyl chloride
• Tosyl chloride
• Thionyl chloride
• Calcium chloride
• Ammonium chloride
• Sulfuryl chloride
• (1S)-(+)-Camphor-10-sulphonic acid
• (+)-GALLOCATECHIN