Oleic-DBCO Chemical Properties

Boiling point:

761.9±60.0 °C(Predicted)

Density 

1.07±0.1 g/cm3(Predicted)

storage temp. 

Storage temp. -20°C

solubility 

Soluble in DMSO, DCM, DMF

form 

Oil

pka

15.74±0.46(Predicted)

color 

Colorless to light yellow

Oleic-DBCO Usage And Synthesis

Uses

Oleic-DBCO is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Oleic-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Oleic-DBCO(2279951-78-7)Related Product Information

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• Cy5 DBCO
• Azadibenzocyclooctyne-Biotin conjugate
• DBCO-C-PEG1
• DBCO-C6-acid
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• DBCO-(CH2)2-NH2-CO-(CH2)2COOH
• DBCO-amine
• DBCO-NHS Ester
• DBCO-(CH2)2-NH2-CO-(CH2)3COOH
• DBCO-(CH2)3-Acid