β-Tocopherol
β-Tocopherol Basic information
- Product Name:
- β-Tocopherol
- Synonyms:
-
- 5,8-DIMETHYLTOCOL
- RAC-BETA-TOCOPHEROL
- beta-tocopherol
- 3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
- Tocopherol,rac-b-
- (2R)-2,5,8-trimethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol
- rac-beta-Tocopherol (5,8-DiMethyltocol)
- β-Tocopherol (Racemic Mixture)
- CAS:
- 148-03-8
- MF:
- C28H48O2
- MW:
- 416.68
- EINECS:
- 205-708-5
- Product Categories:
-
- TF - TOChromatography
- Alphabetic
- Food&Beverage Standards
- Vitamins/CoFactors/Enzymes
- Mol File:
- 148-03-8.mol
β-Tocopherol Chemical Properties
- Melting point:
- <25℃
- Boiling point:
- 474.94°C (rough estimate)
- Density
- 0.9882 (rough estimate)
- refractive index
- 1.4480 (estimate)
- Flash point:
- -23 °C
- storage temp.
- 2-8°C
- solubility
- Chloroform (Sparingly), Ethanol (Slightly), Ethyl Acetate (Slightly), Methanol (
- pka
- 11.05±0.40(Predicted)
- form
- Oil
- color
- Colourless to Yellow
- InChIKey
- WGVKWNUPNGFDFJ-UHFFFAOYSA-N
- LogP
- 10.724 (est)
- EPA Substance Registry System
- 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-rel- (148-03-8)
Safety Information
- Hazard Codes
- F,Xn,N
- Risk Statements
- 11-38-48/20-51/53-62-67-65
- Safety Statements
- 36/37-61-62-16
- RIDADR
- UN1208 3/PG 2
- WGK Germany
- 3
β-Tocopherol Usage And Synthesis
Description
(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an EC50 value of 68.2 μM. (±)-β-Tocopherol (100 μM) inhibits LPS-induced COX-2 gene expression in mouse RAW 264.7 macrophage cells. Unlike (±)-α-tocopherol , (±)-β-tocopherol does not inhibit smooth muscle cell proliferation, decrease PKC activity, increase phosphoprotein phosphatase 2A (PP2A) activity, or modify expression of the α-tropomyosin gene. [Matreya, LLC. Catalog No. 1071]
Uses
One of the naturally occurring forms of Vitamin E. Is biologically less active than α-Tocopherol. This is the racemic mixture of all stereoisomers.
Definition
ChEBI: Beta-tocopherol is a tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts. It has a role as a plant metabolite and a food component. It is a vitamin E and a tocopherol.
β-TocopherolSupplier
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β-Tocopherol(148-03-8)Related Product Information
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- D-α-Tocopherol succinate
- Vitamin E nicotinate
- DL-ALPHA-TOCOPHEROL HYDROGEN SUCCINATE
- DL-α-Tocopherol
- (R,R,R)-γ-Tocopherol, 7,8-Dimethyltocol
- Vitamin E
- (+/-)-ALPHA-TOCOPHEROL PHOSPHATE DISODIUM SALT
- EPC-K(1)
- RAC-5,7-DIMETHYLTOCOL,5,7-Dimethyltocol
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- Tocofibrate
- Tocofenoxate