(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline Chemical Properties

Melting point:

80-82°C

Boiling point:

338°C

Density 

1.065

Flash point:

167°C

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)

form 

Solid

pka

8.91±0.40(Predicted)

color 

White to Off-White

CAS DataBase Reference

118864-75-8(CAS DataBase Reference)

Safety Information

HS Code 

2933.49.7000

(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline Usage And Synthesis

Chemical Properties

White Solid

Uses

Labelled Solifenacin intermediate

Uses

Solifenacin (S676700) intermediate.

Uses

(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline has been used as a lead compound for the development of drugs with dopamine β-hydroxylase inhibitory activity. In vitro studies have shown that 1-phenyl-1,2,3,4-tetrahydro-isoquinoline inhibits human serum dopamine β-hydroxylase and can be used to study the possible role of this enzyme in Parkinson's disease. 

(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline(118864-75-8)Related Product Information

• Phenyl salicylate
• Diphenyl ether
• PHENYL VALERATE
• Tetrahydrofuran
• 1-Phenyl-2-nitropropene
• 5,6,7,8-TETRAHYDROISOQUINOLINE
• 1,2,3,4-Tetrahydroquinoline
• 1,2,3,4-TETRAHYDROISOQUINOLINE
• Tetraphenylcyclopentadienone
• TPP
• 1-PHENYL-2-PROPANOL
• Isoquinoline
• 1-Phenyl-1,2,3,4-tetrahydro-isoquinoline
• Solifenacin Related Compound 18
• 1-Phenyl-3,4-dihydroisoquinoline
• Solifenacin N-Oxide
• Solifenacin Impurity 1 HCl
• Solifenacin Related CoMpound 4 Succinate