ChemicalBook > Product Catalog > API > Antiparasitic drugs > Antiparasitic drugs > N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO
N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO
N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO Basic information
- Product Name:
- N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO
- Synonyms:
-
- N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO SODIUM MONOHYDRATE
- SULFACHLOROPYRAZINE SODIUM
- SULFACHLOROPYRAZINE SODIUM H2O
- SULFACHLORPYRAZINE SODIUM
- sulfaclozine
- SULFACLOZINE SODIUM
- SPZ
- SULFACHLOROPYRAZINE SODIUM(SPZ):N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO SODIUM MONOHYDRATE
- CAS:
- 102-65-8
- MF:
- C10H9ClN4O2S
- MW:
- 284.72
- EINECS:
- 203-044-0
- Product Categories:
-
- pharmaceutical
- Pharmaceutical intermediate
- 1
- 102-65-8
- Mol File:
- 102-65-8.mol
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N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO Chemical Properties
- Melting point:
- 234.8-235.4 °C
- Boiling point:
- 495.7±55.0 °C(Predicted)
- Density
- 1.588±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
- form
- Solid
- pka
- 4.83±0.10(Predicted)
- color
- White to Off-White
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N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO Usage And Synthesis
Uses
Sulfachloropyrazine sodium monohydrate is an antiprotozoal useful in coccidiosis research.
in vivo
Sulfaclozine (60 mg/kg; intravenous injection or oral administration; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract rather than for the treatment of systemic infections[1].
| Animal Model: | 14 male broiler chickens (30-day-old)[1] |
| Dosage: | 60 mg/kg |
| Administration: | Intravenous injection or oral administration (Pharmacokinetic Analysis) |
| Result: | Serum drug concentrations at 0.083, 0.50, 2, 6, 24 and 72h were determined to be 99.62, 83.50, 72.68, 58.43, 38.66 and 13.14 μg/mL, respectively, by intravenous injection. By oral administration were determined as 4.33, 7.95, 16.46, 22.88, 16.03 and 5.74 μg/mL, respectively. |
IC 50
Coccidia
N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO Supplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- 021-50182298 021-50180596
- sales@boylechem.com
Chembest Research Laboratories Limited
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- +86-21-20908456
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Beijing HwrkChemical Technology Co., Ltd
- Tel
- 18515581800 18501085097
- sales.bj@hwrkchemical.com
Shanghai Longsheng chemical Co.,Ltd.
- Tel
- 021-58099652-8005 13585536065
- bin.wu@shlschem.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
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N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO (102-65-8)Related Product Information
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- NSC25872#NSC41835
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- N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO