Ademethionine 1,4-Butanedisulfonate Chemical Properties

Melting point:

>48oC (dec.)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)

form 

Solid

color 

Off-White

Stability:

Hygroscopic

InChIKey

PVCDYZJGZPCASW-FGEWMKOMNA-M

SMILES

C(CCCS(O)(=O)=O)S(O)(=O)=O.O[C@@H]1[C@@H]([C@@H](C[S+](C)CC[C@H](N)C(=O)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O.C(CCCS([O-])(=O)=O)S([O-])(=O)=O |&1:13,14,15,21,27,r|

CAS DataBase Reference

101020-79-5(CAS DataBase Reference)

Ademethionine 1,4-Butanedisulfonate Usage And Synthesis

Description

Ademethionine 1,4-Butanedisulfonate (S-Adenosyl-L-methionnine 1,4-butanedisulfonate) is the 1,4-butanedisulfonate of S-adenosylmethionine (SAM, SAMe). It is clinically used to treat depression, arthritis, liver dysfunction and other diseases. It is suitable for intrahepatic cholestasis before cirrhosis and caused by cirrhosis; it is suitable for intrahepatic cholestasis during pregnancy.

Uses

Ademethionine 1,4-Butanedisulfonate is used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts.

Uses

Adenosine 1,4-butanedisulfonate sodium (SAMe) enteric-coated tablets are widely used to treat preciosis and intrahepatic cholestasis in cirrhosis, and can be used to treat intrahepatic cholestasis (ICP) during pregnancy.

Ademethionine 1,4-Butanedisulfonate(101020-79-5)Related Product Information

• 6-Aminocaproic acid
• Glycine
• ALTRENOGEST
• S-ADENOSYL-L-METHIONINE
• Adenosine
• S-adenosylmethionine
• Tris(hydroxymethyl)aminomethane
• L-Methionine
• S-Adenosyl-L-methionine
• Lignin Sulfonate
• Sulfonates
• L-ETHIONINE
• 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE
• (R, S)-Adenosyl-L-Methionine
• ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL&
• ADENOSINE5'-MONOPHOSPHATESODIUMSALT
• 4'-ethynyl-2-fluoro-2'-deoxyadenosine
• DL-METHIONINE-3,3,4,4-D4