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4,4'-propylenebis(piperazine-2,6-dione)

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4,4'-propylenebis(piperazine-2,6-dione) Basic information

Product Name:
4,4'-propylenebis(piperazine-2,6-dione)
Synonyms:
  • 4,4'-propylenebis(piperazine-2,6-dione)
  • 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
  • RAZOXANUM
  • 4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
  • 4,4'-Propane-1,2-diyldipiperazine-2,6-dione
  • Propyliminum
  • 4-[3-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
  • 4,4'-(Propane-1,2-diyl)
CAS:
21416-67-1
MF:
C11H16N4O4
MW:
268.27
EINECS:
244-379-2
Product Categories:
  • Angiogenesis and metastasis.
Mol File:
21416-67-1.mol
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4,4'-propylenebis(piperazine-2,6-dione) Chemical Properties

Melting point:
237-239°
Boiling point:
411.43°C (rough estimate)
Density 
1.2576 (rough estimate)
refractive index 
1.6081 (estimate)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO: soluble40mg/mL
form 
solid
pka
11.00±0.20(Predicted)
Water Solubility 
3g/L(25 ºC)
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Safety Information

WGK Germany 
3
RTECS 
TL6389900
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4,4'-propylenebis(piperazine-2,6-dione) Usage And Synthesis

Uses

Razoxane is an inhibitor of Topo II.

Definition

ChEBI: Razoxane is a N-alkylpiperazine.

Safety Profile

Suspected human carcinogen producing leukemia and skin tumors. Moderately toxic by intraperitoneal route. Human effects: normocytic anemia and thrombocytopenia. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

4,4'-propylenebis(piperazine-2,6-dione) Supplier

Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Email
sales@boylechem.com
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Email
sales@chemreagents.com
VDM Biochemicals
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0330-2528181
Email
sales@vdmbio.com
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
DebyeTec.com Inc.
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18086626237 18086626237
Email
sales@debyesci.com
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4,4'-propylenebis(piperazine-2,6-dione) (21416-67-1)Related Product Information