6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine dihydrochloride Chemical Properties

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

Appearance

Off-white to light brown Solid

InChI

InChI=1S/C7H8N2.ClH/c1-2-6-4-8-5-7(6)9-3-1;/h1-3,8H,4-5H2;1H

InChIKey

OLSODEICZBRTGO-UHFFFAOYSA-N

SMILES

C12C=CC=NC=1CNC2.Cl

Safety Information

HS Code 

2933998090

6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine dihydrochloride Usage And Synthesis

Uses

6,7-Dihydro-5h-pyrrolo[3,4-b]pyridine, HCl

Synthesis

6-(2,4-dimethoxybenzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine (34.9 mmol) was added in a dry flask under nitrogen. Trifluoroacetic acid (27) and triethylsilane were added to the mixture. ml) and triethylsilane (6.0 ml) were added to the reaction mixture. The reaction mixture was stirred. The reaction mixture was heated at 60 ??C for 5 hours. for 5 hours. The volatiles were removed under vacuum to give a viscous oil. HCl (4 M in dioxane, 40 ml) was added to the residue, followed by ethyl acetate (50 ). ml). The reaction mixture was stirred vigorously for about 1 h at room temperature to provide a precipitate. The solid was separated by filtration. Wash the solid with ethyl acetate (25 ml). Vacuum dry the solid.

6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine dihydrochloride(147740-02-1)Related Product Information

• Tetrahydropyran
• 6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine
• 6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine