ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Pyridine compound > Pyridine derivatives > Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate
Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate
Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Basic information
- Product Name:
- Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate
- Synonyms:
-
- Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate
- Methyl 2-hydroxypyridine-4-carboxylate
- Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate 98%
- 4-Pyridinecarboxylicacid,1,2-dihydro-2-oxo-,methylester(9CI)
- Methyl 2-oxo-1,2-dihydropyridine-4-carboxylate
- Methyl 2-hydroxypyridine-...
- Methyl 2-hydroxypyridine-4-carboxylate, 1,2-Dihydro-4-(methoxycarbonyl)-2-oxopyridine
- Methyl1,2-dihydro-2-oxopyridine-4-carboxylate98%
- CAS:
- 89937-77-9
- MF:
- C7H7NO3
- MW:
- 153.14
- Product Categories:
-
- blocks
- Pyridines
- CARBOXYLICESTER
- Heterocycle-Pyridine series
- Mol File:
- 89937-77-9.mol
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Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Chemical Properties
- Melting point:
- 211-212 °C
- Boiling point:
- 342.4±42.0 °C(Predicted)
- Density
- 1.263±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- solid
- pka
- 11.02±0.10(Predicted)
- color
- White to off-white
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Safety Information
- Hazard Codes
- Xi
- RIDADR
- UN2811
- Hazard Note
- Irritant
- HS Code
- 2933399990
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Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Usage And Synthesis
Uses
Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate is an ester derivative, mainly used as a pharmaceutical intermediate.
Synthesis
The synthesis method of Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate is as follows: Dissolve 10 g (0.066 mol) of m-nitrobenzaldehyde and 11 g (0.067 mol) of ethyl chloroacetate in 60 ml of benzene, and add 1 ml of piperidine. 1 ml of glacial acetic acid, heated in a water bath, and the water generated in the reaction was continuously removed with a Dean-start water separator. After refluxing for 3h, the benzene was evaporated, 20ml of ether was added to the residue, frozen, crystallized, suction filtered, and dried to give 16.2g of methyl 2-hydroxypyridine-4-carboxylate, yield 82%, mp 92 -96°C.
Methyl 1,2-dihydro-2-oxopyridine-4-carboxylateSupplier
Nantong Flying Pharmtech Co., Ltd. Gold
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Shaoyuan Technology (Shanghai) Co., Ltd. Gold
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Energy Chemical
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Wuhan Chemwish Technology Co., Ltd
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- 86-027-67849912
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Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate(89937-77-9)Related Product Information
- methyl 2-oxo-1,2-dihydropyridine-3-carboxylate
- Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate
- AURORA KA-5535
- SPECS AJ-333/25022077
- ISONICOTINIC ACID, 3-CYANO-1,2-DIHYDRO-2-OXO-, ETHYL ESTER
- ETHYL 1,2-DIHYDRO-6-METHYL-3-NITRO-2-OXO-4-PYRIDEINCARBOXYLATE
- 1,2-Dihydro-1-methyl-3-nitro-2-oxo-4-pyridinecarboxylic acid methyl ester
- ETHYL 3-CYANO-2-HYDROXY-6-METHYLISONICOTINATE