3-HYDROXYHEXADECANOIC ACID METHYL ESTER Chemical Properties

Melting point:

48-49 °C(Solv: ligroine (8032-32-4))

Boiling point:

388.9±15.0 °C(Predicted)

Density 

0.922±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Ethanol: 0.5 mg/mL; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL

form 

A crystalline solid

pka

13.91±0.20(Predicted)

color 

White to off-white

Stability:

Hygroscopic

Safety Information

WGK Germany 

3

MSDS

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3-HYDROXYHEXADECANOIC ACID METHYL ESTER Usage And Synthesis

Description

3-hydroxy Palmitic acid methyl ester (3-hydroxy PAME) is an esterized long-chain fatty acid involved in quorum sensing in R. solanacearum, a bacteria that causes lethal wilting in plants. 3-hydroxy-PAME (175 nM) increases levels of PhcA-regulated virulence factors, greater than 20-, 30-, and 25-fold for EPS I, EGL, and PME, respectively, in the AW1-83 strain of R. solanacearum. [Matreya, LLC. Catalog No. 1740]

Uses

3-Hydroxyhexadecanoic Acid Methyl Ester is a fatty acid ester extracted from the flowers of Trollius chinensis Bunge.

Definition

ChEBI: A fatty acid methyl ester of 3-hydroxypalmitic acid.

References

[1] G.A. ACHARI  R. R. Characterization of bacteria degrading 3-hydroxy palmitic acid methyl ester (3OH-PAME), a quorum sensing molecule of Ralstonia solanacearum[J]. Letters in Applied Microbiology, 2015, 60 5: 447-455. DOI: 10.1111/lam.12389
[2] A B FLAVIER. Identification of 3-hydroxypalmitic acid methyl ester as a novel autoregulator controlling virulence in Ralstonia solanacearum.[J]. Molecular Microbiology, 1997, 26 2: 251-259. DOI: 10.1046/j.1365-2958.1997.5661945.x

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