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Furaltadone hydrochloride

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Furaltadone hydrochloride Basic information

Product Name:
Furaltadone hydrochloride
Synonyms:
  • 5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)-2-oxazolidinonmonohyd
  • 5-(4-MorpholinylMethyl)-3-[[(5-nitro-2-furanyl)Methylene]aMino]-2-oxazolidinone Hydrochloride
  • 5-(MorpholinoMethyl)-3-(5-nitrofurfurylidenaMino)-2-oxazolidone Hydrochloride
  • Furaltadone hydrochlorid
  • Hydrochloric furaltadone
  • 2-Oxazolidinone, 5-(4-morpholinylmethyl)-3-[[(5-nitro-2-furanyl)methylene]amino]-, hydrochloride (1:1)
  • 5-(4-morpholinylmethyl)-3-[(5-nitro-2-furanyl)methylideneamino]-2-oxazolidinone chloride
  • 5-morpholinomethyl-3-(5-nitrofurfurylidine)amino-2-oxazolidinonehydrochlorid
CAS:
3759-92-0
MF:
C13H16N4O6.ClH
MW:
360.75
EINECS:
223-169-4
Product Categories:
  • Pharmaceutical intermediates
  • API
  • Amines
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pharmaceutical intermediate
Mol File:
3759-92-0.mol
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Furaltadone hydrochloride Chemical Properties

Melting point:
>300?C (dec.)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Light Yellow to Yellow
Stability:
Hygroscopic
CAS DataBase Reference
3759-92-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
RIDADR 
3249
WGK Germany 
3
RTECS 
RQ3630000
HazardClass 
6.1(b)
PackingGroup 
III

MSDS

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Furaltadone hydrochloride Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

Antibacterial;Bacterial DNA damage

Uses

Furaltadone Hydrochloride is an antibacterial compound.Environmental contaminants; Food contaminants; Heat processing contaminants

Uses

A metabolite of Nitrofuran in milk. Antibacterial.

in vivo

Furaltadone (3-30 mg/kg, p.o., single dose) reduces the allergic response in IgE-mediated PCA in BALB/c mice by inhibiting mast cell activation and degranulation[3].

Animal Model:IgE-mediated passive cutaneous anaphylaxis (PCA) in BALB/c mice[3]
Dosage:3、10、30 mg/kg
Administration:Oral gavage (p.o.), single dose
Result:Significantly inhibited the allergic response in a dose-dependent manner and reduced mast cell degranulation in the skin.

Furaltadone hydrochlorideSupplier

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