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DL-Tryptophan

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DL-Tryptophan Basic information

Product Name:
DL-Tryptophan
Synonyms:
  • (rs)-tryptophan
  • 2-Amino-3,3’-IndolylpropanoicAcid
  • DL-Trytophan
  • DL-Trytophane
  • DL-TRYPTOPHAN extrapure CHR
  • (±)-α-Amino-3-indolepropionic acid, (±)-2-Amino-3-(3-indolyl)propionic acid, DL-3β-Indolylalanine
  • α-amino-β-indolepropinic acid
  • DL-Tryptoplaan
CAS:
54-12-6
MF:
C11H12N2O2
MW:
204.23
EINECS:
200-194-9
Product Categories:
  • Amino Acids & Derivatives
  • Tryptophan [Trp, W]
  • alpha-Amino Acids
  • Amino Acids
  • Biochemistry
  • Indoles
  • Amino Acids Derivatives
  • Tryptophans
  • Amino Acids
  • Alphabetical Listings
  • Stable Isotopes
Mol File:
54-12-6.mol
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DL-Tryptophan Chemical Properties

Melting point:
289-290 °C (dec.)(lit.)
alpha 
[α]D20 -1～1°(c=1, dil. HCl)
Boiling point:
342.72°C (rough estimate)
Density 
1.1754 (rough estimate)
refractive index 
1.5200 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
methanol: water (7:3): soluble
form 
Powder
pka
2.30±0.10(Predicted)
color 
White to light beige or light yellow
Odor
Odorless
Water Solubility 
10 g/L (20 ºC)
BRN 
86196
Stability:
Stable. Incompatible with strong oxidizing agents, strong acids.
InChIKey
QIVBCDIJIAJPQS-UHFFFAOYSA-N
CAS DataBase Reference
54-12-6(CAS DataBase Reference)
NIST Chemistry Reference
Tryptophane(54-12-6)
EPA Substance Registry System
Tryptophan (54-12-6)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
22-36/37/38-37/38-41
Safety Statements 
24/25-36/37/39-36-26
WGK Germany 
1
RTECS 
YN6129200
F 
8
TSCA 
Yes
HS Code 
29339990

MSDS

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DL-Tryptophan Usage And Synthesis

Chemical Properties

White crystals. Slightly soluble in water; stable in alkaline solution; decomposed by strong acids.

Uses

An amino acid precursor of serotonin and melatonin.

Uses

DL-Tryptophan is an amino acid precursor of serotonin and melatonin. It is a dietary supplement for use as an antidepressant, anxiolytic, and sleep aid. DL-tryptophan also can be used as feed nutrition enhancer, antioxidants.

Definition

ChEBI: An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3.

General Description

Tryptophan is the precursor for 5-hydroxy-tryptamin and an essential α-amino acid. DL-Tryptophan exists as a zwitterion during crystallization.

Biochem/physiol Actions

DL-Tryptophan binding to bovine serum albumin is employed for its affinity based chromatographic purification. Supplementation of tryptophan in diets of rat induce bladder tumor.

Safety Profile

Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NOx.

DL-Tryptophan Preparation Products And Raw materials

Raw materials

Acetic acid glacialSodium sulfateAcetic anhydrideWaterDimethylamineAcroleinStarchPyruvic acidSULFUROUS ACIDformaldehydeIndoleL-AlanineL-Phenylalanine1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl esterInosineL-TyrosineL-TryptophanDL-Serine2-MethylindoleN-[(tert-Butoxy)carbonyl]-D-tryptophanGramineINDOPHENOL2-Acetamidoacrylic acidPyridoxal 5'-phosphateAMINOMALONIC ACID

Preparation Products

L-TryptophanD(+)-Tryptophan

DL-TryptophanSupplier

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