1-Benzothiophene-3-carbaldehyde Chemical Properties

Melting point:

53-57 °C (lit.)

Boiling point:

166 °C/20 mmHg (lit.)

Density 

1.2123 (rough estimate)

refractive index 

1.5500 (estimate)

Flash point:

>230 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

form 

powder to crystal

color 

White to Orange to Green

λmax

302nm(EtOH)(lit.)

CAS DataBase Reference

5381-20-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

1-Benzothiophene-3-carbaldehyde Usage And Synthesis

Chemical Properties

Yellow to brown crystalline powder

Uses

Thianaphthene-3-carboxaldehyde (Benzo[b]thiophene-3-carboxaldehyde) may be used as a starting material in the multi-step synthesis of anthra[2,3-b:7,6-b′]bis[1benzothiophenes (ABBTs).
It may be used in the synthesis of :

• 6-(N,N-dimethylamino)-2-(benzo[b]thiophen-3-yl)quinazolin-4-one
• 6-(pyrrolidin-1-yl)-2-(benzo[b]thiophen-3-yl)quinazolin-4-one
• (Z)-2-(benzo-[b]-thio-phen-3-yl-methyl-ene)-1-aza-bi-cyclo-[2.2.2]-octan-3-one

General Description

Thianaphthene-3-carboxaldehyde, also known as benzo[b]thiophene-3-carboxaldehyde, can be synthesized from 3-methyl-benzo[b]thiophene. It undergoes phosphine-free palladium coupling with aryl halides to form 2-arylbenzo[b]thiophenes.

1-Benzothiophene-3-carbaldehyde(5381-20-4)Related Product Information

• Dibenzothiophene
• 4-Dimethylaminobenzaldehyde
• o-Phthalaldehyde
• Thianaphthene
• 3-Thiophenecarboxaldehyde
• 2-Nitrobenzaldehyde
• p-Anisaldehyde
• 4-Hydroxybenzaldehyde
• Thiophene
• 5-CHLOROBENZOTHIOPHENE
• 2-Aminobenzaldehyde
• 2-Thiophenecarboxaldehyde
• Benzaldehyde
• 3-(METHOXYMETHOXY)BENZALDEHYDE
• POLYTHIOPHENE
• Raloxifene
• 3-Acetyl benz[b]thiophene
• 1-Benzo[b]thiophen-3-yl-2-bromoethan-1-one