2-Acetyl-1-methylpyrrole Chemical Properties

Boiling point:

200-202 °C (lit.)

Density 

1.04 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.542(lit.)

FEMA 

3184 | 1-METHYL-2-ACETYLPYRROLE

Flash point:

155 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

pka

-7.46±0.70(Predicted)

Specific Gravity

1.040

color 

Colorless to Yellow to Orange

Odor

at 100.00 %. earthy

Odor Type

earthy

JECFA Number

1306

BRN 

111887

LogP

0.66

CAS DataBase Reference

932-16-1(CAS DataBase Reference)

NIST Chemistry Reference

Ethanone, 1-(1-methyl-1H-pyrrol-2-yl)-(932-16-1)

EPA Substance Registry System

2-Acetyl-1-methylpyrrole (932-16-1)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29339900

MSDS

• Language:English Provider:2-Acetyl-1-methylpyrrole
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Acetyl-1-methylpyrrole Usage And Synthesis

Description

May be prepared from Af-methyl pyrrole and Grignard reagent; by acetylation of 1-methyl-pyrrole.

Chemical Properties

CLEAR COLOURLESS TO LIGHT BROWN LIQUID

Occurrence

Reported found as a component in coffee aroma, asparagus, crispbread, cooked beef, black tea, okra and clam.

Uses

2-Acetyl-1-methylpyrrole was employed as model pyrrole to investigate the antioxidative activity of nonenzymatic browning reactions. It was employed as catalyst for the sulfonylation of spectinomycin.

Definition

ChEBI: A pyrrole carrying methyl and acetyl substituent at the 1- and 2-positions respectively.

Preparation

From N-methyl pyrrole and Grignard reagent; by acetylation of 1-methyl-pyrrole.

Aroma threshold values

Detection: 100 ppb

Synthesis Reference(s)

Synthetic Communications, 21, p. 557, 1991 DOI: 10.1080/00397919108016783

General Description

Reduction of 2-acetyl-1-methylpyrrole with sodium borohydride has been investigated.

2-Acetyl-1-methylpyrrole(932-16-1)Related Product Information

• Acetylacetone
• Methanol
• Tetraacetylethylenediamine
• Acetyl chloride
• N-Methyl-2-pyrrolidone
• 2-Acetyl pyrrole
• Methyl acetate
• Methylparaben
• Methyl acrylate
• Kresoxim-methyl
• Acetonitrile
• Basic Violet 1
• Paraquat dichloride
• N-ACETYL-L-TYROSINE ETHYL ESTER
• Methyl
• Tolmetin sodium
• Sodium tolmetin dihydrate
• 3-ACETYL-1-METHYLPYRROLE