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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Basic information

Product Name:
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
Synonyms:
  • TIMTEC-BB SBB003016
  • 1-CYCLOPROPYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLONE-3-CARBOXYLIC ACID
  • 1-CYCLOPROPYL-6-FLUORO-7-CHLORO-1,4-DIHYDRO-4-OXO-3-QUINOLINIC CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-1,4-DIHYDRO-6-FLUOROQUINOL-4-ONE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXOHYDROQUINOLINE-3-CARBOXYLIC ACID
CAS:
86393-33-1
MF:
C13H9ClFNO3
MW:
281.67
EINECS:
405-050-0
Product Categories:
  • alkyl chloride | alkyl Fluorine| carboxylic acid
  • Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocycles
  • Metabolites & Impurities
  • Ciprofloxacin
  • 86393-33-1
Mol File:
86393-33-1.mol
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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Chemical Properties

Melting point:
242-245 °C(lit.)
Boiling point:
467.3±45.0 °C(Predicted)
Density 
1.652±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
pka
6.36±0.41(Predicted)
color 
Off-White to Light Yellow
InChIKey
ISPVACVJFUIDPD-UHFFFAOYSA-N
CAS DataBase Reference
86393-33-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-52/53
Safety Statements 
26-36-61-22
WGK Germany 
2
RTECS 
VB1993795
HazardClass 
IRRITANT
HS Code 
29334900

MSDS

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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Usage And Synthesis

Chemical Properties

Off-White Crystalline Powder

Uses

An intermediate in the synthesis of Ciprofloxacin, a fluorinated quinolone antibacterial

Uses

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid (Ciprofloxacin EP Impurity A) is a metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.

General Description

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, also known as fluoroquinolonic acid, can be prepared from ethyl 2,4-dichloro-5-fluorobenzoylacetate. It is formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Preparation Products And Raw materials

Preparation Products

Cyhalothrin

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidSupplier

-Binhai Golden Hilen Medicine Chemistry Co., Ltd. Gold
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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid(86393-33-1)Related Product Information