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TRIS(TRIMETHYLSILYL)PHOSPHITE

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TRIS(TRIMETHYLSILYL)PHOSPHITE Basic information

Product Name:
TRIS(TRIMETHYLSILYL)PHOSPHITE
Synonyms:
  • Phosphorous acid, tristrimethylsilyl
  • Tris(trimethylsily)phosphite
  • TRIS(TRIMETHYLSILYL)PHOSPHITE
  • PHOSPHOROUS ACID TRIS(TRIMETHYLSILYL) ESTER
  • Phosphorousacidtrimethylsilylester
  • TRIS(TRIMETHYLSILYL) PHOSPHITE 95%
  • TRIS(TRIMETHYLSILYL)PHOSPHITE 97+%
  • Phosphorous acid tri(trimethylsilyl) ester
CAS:
1795-31-9
MF:
C9H27O3PSi3
MW:
298.54
Product Categories:
  • Si (Classes of Silicon Compounds)
  • Silicon Compounds (for Synthesis)
  • Silyl Esters
  • Si-O Compounds
  • Synthetic Organic Chemistry
Mol File:
1795-31-9.mol
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TRIS(TRIMETHYLSILYL)PHOSPHITE Chemical Properties

Boiling point:
78-81 °C/8 mmHg (lit.)
Density 
0.893 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.409(lit.)
Flash point:
>230 °F
form 
Liquid
Specific Gravity
0.893
color 
Clear colorless
Water Solubility 
Sparingly soluble in water.
Sensitive 
Air & Moisture Sensitive
Hydrolytic Sensitivity
8: reacts rapidly with moisture, water, protic solvents
BRN 
2043814
InChI
InChI=1S/C9H27O3PSi3/c1-14(2,3)10-13(11-15(4,5)6)12-16(7,8)9/h1-9H3
InChIKey
VMZOBROUFBEGAR-UHFFFAOYSA-N
SMILES
[Si](C)(C)(OP(O[Si](C)(C)C)O[Si](C)(C)C)C
CAS DataBase Reference
1795-31-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26-36
RIDADR 
1760
WGK Germany 
3
10-21
TSCA 
No
HazardClass 
8
PackingGroup 
III
HS Code 
29319000

MSDS

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TRIS(TRIMETHYLSILYL)PHOSPHITE Usage And Synthesis

Uses

Tris(trimethylsilyl) Phosphite is used in the studies of bisphosphonic acids as effective inhibitor of glutamine synthetase, a promising approach for the discovery of novel drugs against tuberculosis. It also acts as a reagent in the preparation of substituted calix[4]arenes bearing one or two α-hydroxymethylphosphonic acid fragments at upper rim of macrocycle as inhibitors of glutathione S-transferase in vitro.

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