4-Hydroxy Duloxetine b-D-Glucuronide
4-Hydroxy Duloxetine b-D-Glucuronide Basic information
- Product Name:
- 4-Hydroxy Duloxetine b-D-Glucuronide
- Synonyms:
-
- 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthalenyl b-D-Glucopyranosiduronic Acid
- 4-Hydroxy Duloxetine b-D-Glucuronide
- DULOXETINE-4-HYDROXY-GLUCURONIDE
- 4-Hydroxy Duloxetine β-D-Glucuronide SodiuM Salt
- LY 550408
- 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthalenyl -D-Glucopyranosiduronic Acid
- 4-Hydroxy Duloxetine -D-Glucuronide
- Duloxetine-4-hydroxy-D-glucuronide
- CAS:
- 741693-83-4
- MF:
- C24H27NO8S
- MW:
- 489.542
- Product Categories:
-
- Chiral Reagents
- Glucuronides
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Sulfur & Selenium Compounds
- Mol File:
- 741693-83-4.mol
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4-Hydroxy Duloxetine b-D-Glucuronide Chemical Properties
- Melting point:
- >190°C (dec.)
- Boiling point:
- 781.8±60.0 °C(Predicted)
- Density
- 1.450±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- pka
- 2.76±0.70(Predicted)
- form
- Solid
- color
- White to Brown
- Stability:
- Hygroscopic
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4-Hydroxy Duloxetine b-D-Glucuronide Usage And Synthesis
Chemical Properties
Tan Solid
Uses
A metabolite of Duloxetine
Uses
4-Hydroxy Duloxetine Glucuronide is a derivative of 4-Hydroxy Duloxetine (H941800), a major metabolite of Duloxetine (D721000), which acts as an antidepressant and a dual serotonin and norepinephrine reuptake inhibitor (SNRI). Exhibits linear pharmacokinetics in mice and is not associated in any drastic changes of blood pressure or heart rate.
Definition
ChEBI: 4-Hydroxy duloxetine glucuronide is a glycoside.
4-Hydroxy Duloxetine b-D-GlucuronideSupplier
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