5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Chemical Properties

Melting point:

2100C (dec)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

solubility 

DMSO, Methanol, Water

form 

Solid

color 

Light Tan

InChI

InChI=1S/C7H9NOS.ClH/c9-7-3-5-4-8-2-1-6(5)10-7;/h3,6,8H,1-2,4H2;1H

InChIKey

PUQKTVAKLPDUAW-UHFFFAOYSA-N

SMILES

O=C1SC2CCNCC2=C1.Cl

CAS DataBase Reference

115473-15-9(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

HazardClass 

IRRITANT

HS Code 

29349990

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Usage And Synthesis

Chemical Properties

Cream Solid

Uses

Solifenacin intermediate

Uses

An intermediate in the synthesis of Prasugrel (P701150).

Synthesis

Hydrochloride (0.32 ml) was added in a solution of 5-Triphenyl methyl-tetrahydro-5, 6, 7,7a 4H- theino-[3,2-c]- pyridone-2 (100 g, 0.25 moles) in acetone (500 ml) at 25 °C. Stir the reaction mass for 1 hr at 50 °C, then cool the reaction mass to 25 °C and stir for 8 to 10 hrs at 25 °C. Filter the product and wash it with acetone. Dry the material under vacuum at 60 °C to obtain 5, 6, 7,7a -Tetrahydro-4H- theino-[3,2-c]- pyridone-2 hydrochloride (42 g, 99percent).

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride(115473-15-9)Related Product Information

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