PSEUDOLARIC ACID B
PSEUDOLARIC ACID B Basic information
- Product Name:
- PSEUDOLARIC ACID B
- Synonyms:
-
- Pseudolaric acid
- Pseudolaric Acid B (PAB)
- Pseudolaric Acid B(PBA)
- -1,3-pentadienyl)3,4,4a,5,6,9-hexahydro-3-methyl-1-oxo-,7-methylester,(3-al
- 1h-4,9a-ethanocyclohepta(c)pyran-7-carboxylicacid,4a-(acetyloxy)-3-(4-carboxy
- pha(1e,3e),4-alpha,4a-alpha,9a-alpha)-(-)-(9ci)
- PSEUDOLARIC ACID B
- PLAB
- CAS:
- 82508-31-4
- MF:
- C23H28O8
- MW:
- 432.46
- EINECS:
- 231-291-4
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Inhibitors
- Mol File:
- 82508-31-4.mol
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PSEUDOLARIC ACID B Chemical Properties
- Melting point:
- 166°C
- Boiling point:
- 466.14°C (rough estimate)
- Density
- 1.2108 (rough estimate)
- refractive index
- 1.4480 (estimate)
- storage temp.
- 2-8°C
- solubility
- methanol: soluble1mg/mL, clear, colorless
- form
- powder or crystals
- pka
- 4.52±0.19(Predicted)
- color
- white to off-white
- InChIKey
- VDGOFNMYZYBUDT-YCONPBHISA-N
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Safety Information
- Hazard Codes
- T
- Risk Statements
- 25-62
- Safety Statements
- 36/37-45-24/25
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
- HS Code
- 29329990
- Hazardous Substances Data
- 82508-31-4(Hazardous Substances Data)
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PSEUDOLARIC ACID B Usage And Synthesis
Description
Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer therapy, including inducing apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo.
Uses
(-)-Pseudolaric Acid B is a diterpenoid posessing an immunomodulatory effect. It acts as an immunosuppressant in vitro/vivo however does show some cytotoxicity. Anti-tumor agent as well.
Definition
ChEBI: Pseudolaric acid B is a diterpene lactone.
PSEUDOLARIC ACID BSupplier
Cheng Du Pufeide Biotechnology Co., Ltd. Gold
- Tel
- 028-82610909 13388174823
- scglp@glp-china.com
Shanghai YuanYe Biotechnology Co., Ltd. Gold
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
- sales@BioChemBest.com
Adamas Reagent, Ltd.
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
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PSEUDOLARIC ACID B(82508-31-4)Related Product Information
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- Pseudolaric Acid C
- tert-Butyl trimethylacetate
- METHYL-CIS-4-DECENOATE
- ETHYL 3 ACETOXY HEXANOATE
- 2,4-HEXADIENYL ISOBUTYRATE
- ε-Caprolactone
- MUGUOL
- PSEUDOLARIC ACID B
- ETHYL CIS-2-HYDROXY-1-CYCLOPENTANECARBOXYLATE
- ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE
- 3,3-DIMETHYL-TETRAHYDRO-PYRAN-2-ONE
- CIS-2-HYDROXY-1-CYCLOPENTANECARBOXYLIC ACID,99%
- HEX-2-ENEDIOIC ACID DIMETHYL ESTER
- ETHYL (1R,2S)-CIS-2-HYDROXYCYCLOPENTANECARBOXYLATE
- SEBACIC ACID MONOMETHYL ESTER
- 2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER
- Pseudolaric Acid B, Pseudolarix kaempferi