ditophal
ditophal Basic information
- Product Name:
- ditophal
- Synonyms:
-
- 1,3-Benzenedicarbothioic acid 1S,3S-diethyl ester
- Diethyl dithiolisophthalate
- ETIP
- ditophal
- ETISUL
- 1,3-Benzenedicarbothioic acid, S,S-diethyl ester
- CAS:
- 584-69-0
- MF:
- C12H14O2S2
- MW:
- 254.37
- Mol File:
- 584-69-0.mol
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ditophal Usage And Synthesis
Originator
ICI 15688,ICI
Manufacturing Process
33 parts of diethyl sulphate are added to 20 parts of diethiolisophthalic acid (MP 245°-247°C prepared by the reaction of isophthalylchloride with sodium hydrogen sulphide) in 125 parts of 8% aqueous sodium hydroxide solution at 20°C and the mixture is then heated at 40°-50°C during one hour. The mixture is then cooled and extracted with 250 parts of benzene, in three portions. The benzene extract is washed with water and dried and the benzene is distilled. The residue is then distilled under reduced pressure to give diethyl dithioisophthalate, BP 210°-215°C/15 mm.
Therapeutic Function
Leprostatic