Miroprofen
Miroprofen Basic information
- Product Name:
- Miroprofen
- Synonyms:
-
- 2-[4-(Imidazo[1,2-a]pyridin-2-yl)phenyl]propionic acid
- 2-[p-(Imidazo[1,2-a]pyridin-2-yl)phenyl]propionic acid
- 4-(Imidazo[1,2-a]pyridin-2-yl)-α-methylbenzeneacetic acid
- 4-Imidazo[1,2-a]pyridin-2-yl-α-methylbenzeneacetic acid
- Y-9213
- OJGQFYYLKNCIJD-UHFFFAOYSA-N
- Miroprofene
- Benzeneacetic acid, 4-imidazo[1,2-a]pyridin-2-yl-α-methyl-
- CAS:
- 55843-86-2
- MF:
- C16H14N2O2
- MW:
- 266.29
- Mol File:
- 55843-86-2.mol
Miroprofen Chemical Properties
- Boiling point:
- 409.5°C (rough estimate)
- Density
- 1.1262 (rough estimate)
- refractive index
- 1.6240 (estimate)
- pka
- 3.79±0.10(Predicted)
Miroprofen Usage And Synthesis
Uses
Miroprofen (Y 0213) is an orally active nonsteroidal anti-inflammatory analgesic (NSAID). Miroprofen exhibits anti-inflammatory, analgesic and anti-platelet activities[1][2][3].
Definition
ChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(imidazo[1,2-a]pyridin-2-yl)phenyl group. A non-steroidal anti-inflammatory drug that also exhibits analgesic, antipyretic and plate et aggregation inhibition properties.
References
[1] Mikashima H, et al., [Inhibitory effect of 2-(4-(2-imidazo(1,2-a)pyridyl)phenyl) propionic acid (miroprofen) on platelet aggregation and prostaglandin I2 generation (author's transl)]. Yakugaku Zasshi. 1982 Jan;102(1):99-103. Japanese. PMID:7045328
[2] Sakaizumi K, et al., [Analgesic effects of miroprofen in post-extraction pain]. Shikai Tenbo. 1983 May;61(5):1021-6. Japanese. PMID:6603669
[3] Katsu M, et al., [Double blind controlled study of miroprofen in acute upper respiratory tract infections--comparison with ibuprofen]. Kansenshogaku Zasshi. 1982 May;56(5):434-53. Japanese. DOI:10.11150/kansenshogakuzasshi1970.56.434