Onitin Chemical Properties

Melting point:

212 °C

Boiling point:

445.3±45.0 °C(Predicted)

Density 

1.156±0.06 g/cm3(Predicted)

pka

9.76±0.40(Predicted)

LogP

2.920 (est)

Onitin Usage And Synthesis

Uses

Onitin is a natural product, that can be isolated from Onychium siliculosum. Onitin is also a non-competitive antagonist of histamine. Onitin shows activity in blocking the peristaltic reflex of the guinea-pig ileum, in inhibition of the responses of guinea-pig ileum to histamine and of inhibition of the responses of guinea-pig tracheal muscle to histamine[1].

References

[1] Wu T S, et al. Flavanone and other constituents from Onychium siliculosum. Phytochemistry, 1981, 20(3):527–529.

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