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PD153035 HCl

Basic information Safety Supplier Related

PD153035 HCl Basic information

Product Name:
PD153035 HCl
Synonyms:
  • PD 153035 hydrochloride, >=98%
  • SU-5271 (AG1517) HCl ,ZM 252868 HCl
  • 6,7-Dimethoxy-4-[N-(3-bromophenyl)amino]quinazoline hydrochloride PD153035
  • 4-Quinazolinamine, N-(3-bromophenyl)-6,7-dimethoxy-, monohydrochloride
  • 6,7-Dimethoxy-4-[N-(3-bromophenyl)amino]quinazoline hydrochloride
  • PD153035 Hydrochloride (ZM 252868
  • CS-473
  • PD 153035;SU 5271; AG-1517;PD-153035;SU5271; AG 1517
CAS:
183322-45-4
MF:
C16H14BrN3O2.HCl
MW:
0
Product Categories:
  • Inhibitors
Mol File:
183322-45-4.mol
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PD153035 HCl Chemical Properties

Melting point:
265°C(lit.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO: soluble2mg/mL, clear (warmed)
form 
powder
color 
white to beige
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Safety Information

Hazard Codes 
T
Risk Statements 
25-37/38-41
Safety Statements 
26-39-45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HS Code 
2933.59.8000
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PD153035 HCl Usage And Synthesis

Uses

PD153035 is an inhibitor of EGFR, competitive with ATP. EGF Receptor: IC50 = 25 pM (Ki = 6 pM).

Definition

ChEBI: A hydrochloride obtained by combining PD-153035 with one equivalent of hydrochloric acid.

Biological Activity

PD153035 is apotent and selective ATP competitive inhibitor of the epidermal growth factor receptor tyrosine kinase EGFR.

PD153035 HClSupplier

Shanghai Boyle Chemical Co., Ltd.
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Chembest Research Laboratories Limited
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TCI (Shanghai) Development Co., Ltd.
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Jinan Trio PharmaTech Co., Ltd.
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China Langchem Inc.
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