MONASCIN Chemical Properties

Melting point:

145 °C

Boiling point:

574.6±50.0 °C(Predicted)

Density 

1.18±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

form 

Solid

pka

10.59±0.60(Predicted)

color 

Light yellow to yellow

BRN 

51355

InChIKey

XXKNHBAFFJINCK-RVEJDSBJSA-N

Safety Information

WGK Germany 

2

MONASCIN Usage And Synthesis

Uses

Monascin is an azaphilonoid pigment extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration.

Definition

ChEBI: An organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl an methyl groups, respectively (the 3S,3aR,9aR diastereoisomer). One of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mould rice), it is a potent inhibitor of car inogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours.

Biochem/physiol Actions

Monascin is one of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mold rice). It is a potent inhibitor of carcinogenesis measured against chemical or UV initiated, phorbol-promoted mouse skin tumors.

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