Catalpol
Catalpol Basic information
- Product Name:
- Catalpol
- Synonyms:
-
- CATALPOL
- CATAPOL
- ,6-beta,6a-alpha))-
- beta-d-glucopyranoside,1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)
- catalpinoside
- de(p-hydroxybenzoyl)catalposide
- des-p-hydroxybenzoyl-catalposid
- oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl,(1as-(1a-alpha,1b-beta,2-beta,5a-beta
- CAS:
- 2415-24-9
- MF:
- C15H22O10
- MW:
- 362.33
- EINECS:
- 219-324-0
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Inhibitors
- Iridoids
- Mol File:
- 2415-24-9.mol
Catalpol Chemical Properties
- Melting point:
- 203-205°C
- Boiling point:
- 675.6±55.0 °C(Predicted)
- Density
- 1.72±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
- form
- Solid
- pka
- 12.79±0.70(Predicted)
- color
- White to Off-White
- InChIKey
- LHDWRKICQLTVDL-CLLMHHLUSA-N
- LogP
- -4.609 (est)
Catalpol Usage And Synthesis
Description
Catalpol is an iridoid glycoside that has been isolated from R. glutinosa and has diverse biological activities, including anti-apoptotic, pro-angiogenic, and radioprotective properties. It protects against mitochondrial pathway-dependent apoptosis in PC12 rat adrenal pheochromocytoma cells and H9c2 rat embryonic ventricular myocardial cells when used at a concentration of 10 μM. Catalpol pretreatment reduces apoptosis and improves viability in AHH-1 human lymphocyte cells exposed to ionizing radiation and reduces intestinal damage induced by radiation in mice when used at concentrations and doses ranging from of 25 to 100 μg/ml and 25 to 100 mg/kg, respectively. In a rat model of stroke, catalpol (5 mg/kg, i.p.) increases the expression of erythropoietin and VEGF and improves angiogenesis in the brain.
Chemical Properties
Light brown powder
Uses
Catapol is an iridoid glucoside that has been shown to alleviate neuropathic pain.
Definition
ChEBI: Catalpol is an organic molecular entity. It has a role as a metabolite.
CatalpolSupplier
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Catalpol(2415-24-9)Related Product Information
- Palmatine chloride
- alpha-Cyperone
- Verbascoside
- Salicylic acid
- Citric acid
- Ferulic Acid
- Artemisinin
- VERPROSIDE
- PICROSIDE I
- Catalpol
- 6'-VANILLOYL CATALPOL,Vanilloyl catalpol
- Dihydrocatalpol
- 6-O-Cinnamoyl Catalpol
- [(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-[(E)-3-(4-hydroxy-3-methoxyphenyl)propenoyloxy]-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside
- Acetylcatalpol
- gmelinol
- Catalpol std.,CATALPOL(RG)
- CATALPOL(SH)