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2,4-Dichloro-5-methylpyrimidine

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2,4-Dichloro-5-methylpyrimidine Basic information

Product Name:
2,4-Dichloro-5-methylpyrimidine
Synonyms:
  • 2,4-dichloro-5-methyl-pyrimidin
  • 2,4-Dichloro-5-methyl-1,3-diazine
  • Dichloro-5-MethylpyriMid
  • 2,4-DICHLORO-5-METHYLPYRIMIDINE
  • 2,4-Dichloro-5-methylpyrimidine **Toxic, Stench**
  • Toxic,stench
  • PYRIMIDINE,2,4-DICHLORO-5-METHYL
  • 2,4-Dichloro-5-
CAS:
1780-31-0
MF:
C5H4Cl2N2
MW:
163
EINECS:
217-227-8
Product Categories:
  • Heterocycle-Pyrimidine series
  • C4 to C5
  • pharmacetical
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Halides
  • Nucleic acids
  • Bases & Related Reagents
  • Nucleotides
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • PyrimidinesHeterocyclic Building Blocks
  • Heterocycles
  • Pyrimidine
  • Building Blocks
  • Halogenated
  • Nucleotides and Nucleosides
  • Pyrimidines
Mol File:
1780-31-0.mol
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2,4-Dichloro-5-methylpyrimidine Chemical Properties

Melting point:
26-28 °C (lit.)
Boiling point:
108-109 °C/11 mmHg (lit.)
Density 
1.39 g/mL at 25 °C (lit.)
refractive index 
1.6300 (estimate)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in chloroform, ether, ethyl acetate and toluene
pka
-2.44±0.29(Predicted)
form 
powder to lump to clear liquid
color 
White or Colorless to Almost white or Almost colorless
Sensitive 
Lachrymatory
InChIKey
DQXNTSXKIUZJJS-UHFFFAOYSA-N
CAS DataBase Reference
1780-31-0(CAS DataBase Reference)
EPA Substance Registry System
Pyrimidine, 2,4-dichloro-5-methyl- (1780-31-0)
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Safety Information

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45-27
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29335990

MSDS

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2,4-Dichloro-5-methylpyrimidine Usage And Synthesis

Chemical Properties

White to Off White Low Melting Solid

Uses

2,4-Dichloro-5-methylpyrimidine, is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine. It can react with piperidineto produce 2-chloro-5-methyl-4-piperidin-1-yl-pyrimidine. This reaction will need solvent dioxane.

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