2-Methyl-5-nitrobenzenesulfonamide Chemical Properties

Melting point:

197-199

Boiling point:

431.4±55.0 °C(Predicted)

Density 

1.475±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Sparingly), Methanol (Slightly)

form 

Solid

pka

9.56±0.60(Predicted)

color 

Yellow to Dark Yellow

CAS DataBase Reference

6269-91-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Hazard Note 

Irritant

HS Code 

2935909099

2-Methyl-5-nitrobenzenesulfonamide Usage And Synthesis

Uses

2-Methyl-5-nitrobenzenesulfonamide is a chemical reagent in the synthesis of good inhibitors of cancer-related carbonic anhydrase. Also used in the synthesis of novel deacetylase inhibitors used in anti-tumor therapy.

structure and hydrogen bonding

In the 2-Methyl-5-nitrobenzenesulfonamide, C7H8N2O4S, the nitro group is twisted by 9.61 (2)° relative to the benzene ring. In the crystal, mol-ecules are linked by N—H…O and N—H…(O, O) hydrogen bonds between the amino and sulfonyl groups, forming layers parallel to (001)[1].

References

[1] Muhammad Zia-Ur-Rehman. “2-Methyl-5-nitro-benzene-sulfonamide.” Acta crystallographica. Section E, Structure reports online 66 Pt 1 (2009): o136.

2-Methyl-5-nitrobenzenesulfonamide(6269-91-6)Related Product Information

• N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine
• N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine
• Pazopanib Related Compound 2
• Pazopanib Impurity 9
• 1,3-DiMethyl-6-aMino-1H-indazole
• 2,3-dimethyl-2H-indazol-6-amine hydrochloride
• 3-Methyl-6-nitro-2H-indazole
• Pazopanib Related Compound 3
• Pazopanib Impurity 2
• 3-AMINO-4-METHYLBENZENESULFONAMIDE
• Pazopanib Impurity 3
• 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE
• 1,3-Dimethyl-6-nitro-1H-indazole
• Pazopanib
• Pazopanib Impurity 8
• Pazopanib Impurity 10
• Pazopanib Impurity 4
• Pazopanib Impurity 9