4-Chlorothiophenol Chemical Properties

Melting point:

49-51 °C(lit.)

Boiling point:

205-207 °C(lit.)

Density 

1.1911

refractive index 

1.5480

Flash point:

>230 °F

storage temp. 

2-8°C

solubility 

methanol: soluble

pka

pK1:5.9 (25°C)

form 

Crystalline Solid

color 

White to almost white

Water Solubility 

insoluble

Sensitive 

Stench/Lachrymatory

BRN 

605971

InChIKey

VZXOZSQDJJNBRC-UHFFFAOYSA-N

CAS DataBase Reference

106-54-7(CAS DataBase Reference)

NIST Chemistry Reference

Benzenethiol, 4-chloro-(106-54-7)

EPA Substance Registry System

Benzenethiol, 4-chloro- (106-54-7)

Safety Information

Hazard Codes 

C

Risk Statements 

22-34-36/37-20/21/22

Safety Statements 

26-36/37/39-45-27

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

RTECS 

DC1050000

F 

9-13-23

Hazard Note 

Corrosive/Lachrymatory/Stench

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29309090

MSDS

• Language:English Provider:4-Chlorothiophenol
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Chlorothiophenol Usage And Synthesis

Chemical Properties

white to almost white crystalline solid

Uses

Oil additives, agricultural chemicals, plasticizers, rubber chemical, dyes, wetting agents, and stabilizers.

Uses

4-Chlorothiophenol was used to modify poly(vinyl chloride) and to synthesize poly(vinyl chloride) with halogen groups.

Synthesis Reference(s)

The Journal of Organic Chemistry, 27, p. 4455, 1962 DOI: 10.1021/jo01059a081
Synthetic Communications, 18, p. 575, 1988 DOI: 10.1080/00397918808064014

General Description

4-Chlorothiophenol undergoes oxidative coupling catalyzed by iron(III)-tetra phenyl prophyrin to form disulfides.

Hazard

Toxic by ingestion.

Purification Methods

Recrystallise the thiophenol from aqueous EtOH. The SMe ether has m 129o and the SEt ether has m 64o. [D'Sousa et al. J Org Chem 52 1720 1987, Beilstein 6 H 326, 6 I 149, 6 III 1034.]

4-Chlorothiophenol(106-54-7)Related Product Information

• 4-Chlorotoluene
• 4-Chlorobenzyl chloride
• METHYL MERCAPTAN
• 4-Chlorophenol
• Tetrachloroterephthalonitrile
• 4-(Chloromethyl)benzoic acid
• 4-Chloroaniline
• 4,4'-Thiobis-phenol
• Thiophenol
• SODIUM THIOPHENOXIDE
• 4-Chlorobenzenesulfonyl chloride
• Sulfenone
• 2-Chlorothioxanthone
• 2-Chlorophenothiazine
• 3,4-DICHLOROTHIOPHENOL
• 4,4'-Dichlorodiphenyl sulfone
• 2,4,5-TRICHLOROBENZENESULFONYL CHLORIDE
• 2-CHLORO-5-(FLUOROSULFONYL)BENZOIC ACID