YO-PRO 1 Chemical Properties

Melting point:

>250 ℃

storage temp. 

2-8°C

solubility 

H2O: soluble5, clear (warmed)

form 

powder

color 

yellow to orange-brown

λmax

491 nm

Biological Applications

Nucleic acid hybridization; nucleic acid sequencing; detecting nucleic acids,cells,bacteria,immunodeficiency virus,microorganisms; counting embryoblasts,viruses; apoptosis assay; white blood cell functional assay

Safety Information

RIDADR 

UN 2811 6.1 / PGIII

YO-PRO 1 Usage And Synthesis

Definition

ChEBI: An unsymmetrical C1 cyanine dye having 1,3-benzoxazol-2-yl and quinolinium-4-yl substituents.

Biochem/physiol Actions

Oxazole yellow is a fluorescent cyanine dye that binds to DNA and is used to detect apoptotic cells. Oxazole yellow does not enter live cells. However, during apoptosis the cytoplasmic membrane becomes slightly permeable, allowing entry of the dye. Oxazole yellow is often used along with propidium iodide (catalog no. P4170), a DNA dead cell stain that does not enter either live or apoptotic cells. The λEx/λEm of Oxazole yellow is 491/509.

storage

-20°C (protect from light)

YO-PRO 1(152068-09-2)Related Product Information

• 2-([1-(3-[[3-(DIMETHYL(3-[4-[(E)-(3-METHYL-1,3-BENZOXAZOL-3-IUM-2-YL)METHYLIDENE]-1(4H)-QUINOLINYL]PROPYL)AMMONIO)PROPYL](DIMETHYL)AMMONIO]PROPYL)-4(1H)-QUINOLINYLIDENE]METHYL)-3-METHYL-1,3-BENZOXAZOL-3-IUM TETRAIODIDE
• YO-PRO 3
• YOYO 3