corynoxeine
corynoxeine Basic information
- Product Name:
- corynoxeine
- Synonyms:
-
- corynoxeine
- (7R,16E,20α)-16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester
- (alphaE,1'R,6'R,7'S,8'aS)-6'-Ethenyl-1,2,2',3',6',7',8',8'a-octahydro-alpha-(methoxymethylene)-2-oxospiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid methyl ester
- 16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester
- Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-aceticacid, 6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-a-(methoxymethylene)-2-oxo-, methyl ester, (aE,1'R,6'R,7'S,8'aS)-
- Corynoxeine, 99.9%
- Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1'R,6'R,7'S,8'aS)-
- corynoxeine USP/EP/BP
- CAS:
- 630-94-4
- MF:
- C22H26N2O4
- MW:
- 382.46
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 630-94-4.mol
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corynoxeine Chemical Properties
- Melting point:
- 210℃
- Boiling point:
- 562.7±50.0 °C(Predicted)
- Density
- 1.25
- solubility
- DMSO:27.87(Max Conc. mg/mL);72.87(Max Conc. mM)
- pka
- 13.54±0.60(Predicted)
- form
- Powder
- color
- White to off-white
- InChIKey
- MUVGVMUWMAGNSY-VAUYTDFQNA-N
- SMILES
- O=C1NC2C=CC=CC=2[C@]21CCN1C[C@H](C=C)[C@@H](/C(=C\OC)/C(=O)OC)C[C@@]21[H] |&1:9,14,17,27,r|
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corynoxeine Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Uncaria rhynchophylla.
Uses
Corynoxeine is an alkaloid isolated from extraction of Uncaria rhynchophylla, is useful in the treatment of vascular diseases and protection against ischemia-induced neuronal damage.
IC 50
ERK1; ERK2
corynoxeineSupplier
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