trichodesmine
trichodesmine Basic information
- Product Name:
- trichodesmine
- Synonyms:
-
- (3R,4R,5R,8a1R,13aR)-4,5-dihydroxy-3-isopropyl-4,5-dimethyl-4,5,8,8a1,10,12,13,13a-octahydro-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione
- 2H-[1,6]Dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione, 4,5,8,10,12,13,13a,13b-octahydro-4,5-dihydroxy-4,5-dimethyl-3-(1-methylethyl)-, (3R,4R,5R,13aR,13bR)-
- CAS:
- 548-90-3
- MF:
- C18H27NO6
- MW:
- 353.41
- Mol File:
- 548-90-3.mol
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trichodesmine Chemical Properties
- Melting point:
- 160-161 °C (decomp)
- Boiling point:
- 546.5±50.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- pka
- 12.19±0.60(Predicted)
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trichodesmine Usage And Synthesis
Uses
Trichodesmine is a pyrrolizidine alkaloid that has neurotoxic effects and is naturally found in Crotolaria argyptiaca, a shrub plant that is native to the south eastern desert of Egypt. Trichodesmine is also known to have toxic effects on pyrrole binding and Glutathione (G597951) metabolism in the rat.
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